Adverse reactions associated with the use of cosmetics include comedones and folliculitis that substantiate the potential of cosmetic products to induce, aggravate or prolong acne. Acne cosmetica is a particular facial variant of acne. It commonly affects young adult women who use cosmetics. Key to the management of acne cosmetica is the avoidance of comedogenic cosmetics. Thus, it is of crucial importance to evaluate cosmetics with respect to their comedogenicity. Methods of assessment include animal models, human models and clinical trials. Among them, the rabbit ear assay, although not ideal, is the best available. Today, most commercial products are safe. However, dermatologists should remain vigilant and provide the guidelines for beneficial use of cosmetics to acne-prone individuals.