Conference Name:European Medical and Biological Engineering Conference
A series of inverted Event-Related
Potential (ERP) signals were analyzed with pattern
recognition methods using new morphological
features and powerful classifiers, in an attempt to
develop a computer-aided discrimination system of
OCD patients from controls. Eighteen OCD patients
and twenty controls were examined. All subjects
were evaluated by a computerized version of the
digit span subtest of the Wechsler Adult Intelligence
Scale. EEGs were recorded from 15 scalp leads, and
they were inverted to intracranial current sources
using the BET-ART method. 60 source locations
were positioned on a spherical shell corresponding to
the outer layers of the cortex. From the P600
component of each signal nineteen waveformfeatures
were calculated. The Probabilistic Neural
Network (PNN) classifier was developed, and it was
fed with feature combinations from all source
locations. Highest overall accuracy (84.2%) was
found at the right frontal brain region indicating
that OCD patients may present deficits related to
working memory mechanisms corresponding to that
region.
Subject:Medicine, Medical technology, Ιατρική, Ιατρικά όργανα και εξοπλισμός