Study of aminoglycoside-nucleic acid interactions by an HPLC method

dc.contributor.author	Κωνσταντίνου-Κόκοτου, Βιολέτα	el
dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.contributor.author	Κοκοτός, Γιώργος	el
dc.date.accessioned	2015-05-09T19:50:49Z
dc.date.available	2015-05-09T19:50:49Z
dc.date.issued	2015-05-09
dc.identifier.uri	http://hdl.handle.net/11400/10045
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.sciencedirect.com/science/article/pii/S0960894X01001159	en
dc.subject	αντιβιοτικά
dc.subject	μέθοδος HPLC
dc.subject	νουκλεϊκά οξέα
dc.subject	aminoglycoside antibiotics
dc.subject	HPLC method
dc.subject	Nucleic acids--Synthesis
dc.title	Study of aminoglycoside-nucleic acid interactions by an HPLC method	en
heal.type	journalArticle
heal.classification	Χημεία
heal.classification	Φαρμακευτική
heal.classification	Chemistry
heal.classification	Pharmacy
heal.classificationURI	N/A-Χημεία
heal.classificationURI	N/A-Φαρμακευτική
heal.classificationURI	http://skos.um.es/unescothes/C00568
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85100603
heal.keywordURI	http://lod.nal.usda.gov/148694
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85093148
heal.identifier.secondary	DOI: 10.1016/S0960-894X(01)00115-9
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2001-04-23
heal.bibliographicCitation	Constantinou-Kokotou, T., Karikas, G. and Kokotos, G. (2001) Study of aminoglycoside-nucleic acid interactions by an HPLC method. Bioorganic & Medicinal Chemistry Letters. [Online] 11 (8). pp.1015-1018. Available from: http://www.sciencedirect.com [Accessed 09/05/2015]	en
heal.abstract	The interactions of a number of aminoglycoside antibiotics with tRNA and DNA were studied by an HPLC method. based on tRNA and DNA peak size exclusion. Among the compounds studied (deoxystreptamine, neamine, neomycin B, kanamycin A, gentamicin A, netilmicin, streptomycin, and the synthetic neamine analogue BKN3), neomycin B and the synthetic analogue of neamine were proved to be the most potent binders.	en
heal.publisher	Elsevier	en
heal.journalName	Bioorganic & Medicinal Chemistry Letters	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true