Potential effects of stress in critical illness through the role of stress neuropeptides

dc.contributor.author	Παπαθανασόγλου, Ελισάβετ Δ.	el
dc.contributor.author	Γιαννακοπούλου, Μαργαρίτα	el
dc.contributor.author	Μπουζίκα, Μερόπη Δ.	el
dc.contributor.author	Μπόζας, Ευάγγελος	el
dc.contributor.author	Καραμπίνης, Ανδρέας	el
dc.date.accessioned	2015-05-12T15:40:43Z
dc.date.available	2015-05-12T15:40:43Z
dc.date.issued	2015-05-12
dc.identifier.uri	http://hdl.handle.net/11400/10212
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://onlinelibrary.wiley.com/doi/10.1111/j.1478-5153.2010.00363.x/full	el
dc.subject	Neurosciences
dc.subject	Comprehensive literature reviews
dc.subject	Ολοκληρωμένη ανασκόπηση της βιβλιογραφίας
dc.subject	Emotional reactions to illness
dc.subject	Συναισθηματικές αντιδράσεις στην ασθένεια
dc.subject	Νευροεπιστήμες
dc.subject	Nursing theory
dc.subject	Νοσηλευτική θεωρία
dc.subject	Psychological care of patients
dc.subject	Ψυχολογική φροντίδα των ασθενών
dc.subject	Psychological issues during and after discharge from intensive care
dc.subject	Ψυχολογικά προβλήματα κατά τη διάρκεια και μετά το εξιτήριο από την εντατική
dc.title	Potential effects of stress in critical illness through the role of stress neuropeptides	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Psychology
heal.classification	Ιατρική
heal.classification	Ψυχολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://zbw.eu/stw/descriptor/15790-5
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Ψυχολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh91006099
heal.identifier.secondary	DOI: 10.1111/j.1478-5153.2010.00363.x
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Νοσηλευτικής	el
heal.publicationDate	2010-07
heal.bibliographicCitation	Papathanassoglou, E. D., Giannakopoulou, M., Mpouzika, M. D., Bozas, E. and Karabinis, A. (2010). Potential effects of stress in critical illness through the role of stress neuropeptides. "Nursing in Critical Care" 15(4). July - August 2010. pp 204–216. Available from: http:http://onlinelibrary.wiley.com/doi/10.1111/j.1478-5153.2010.00363.x/full. [Accessed 15/06/2010]	en
heal.abstract	Aims and objectives: To critically review evidence on the hypothesis that the multitude of cognitive and psychological stressors perceived by critically ill individuals may contribute to the development of pathophysiologic sequlae through modulation of the levels of stress neuropeptides. Background: Critically ill individuals experience high levels of stress and intense adverse emotions. Although psychological stress has long been recognized as a factor in disease, and despite the nursing tenet on the importance of patients' psychological responses, in critical care, the potential physiologic effects of stress have received little attention. Design, Methods: Narrative critical review. Databases searched included Medline, CINAHL, PubMed and the Cochrane Library. Evidence on the role of stress neuropeptides and pertinent findings in critically ill individuals are reviewed. Results: Limbic and extra-limbic brain structures along with specific stress neuropeptides [corticotrophin releasing hormone (CRH), adrenocorticotropin hormone (ACTH), neuropeptide Y , vasopressin, prolactin, oxytocin, substance P, cholecystokinin, endorphins, enkephalins, somatostatin, noradrenaline, melatonin] are involved in emotional and stress responses. Research evidence indicates that stress neuropeptide levels may be altered in critical illness. Moreover, they mediate processes such as immunity, endothelial response and oxidative stress. A framework for future research and practice is presented. Conclusions: It is probable that, in critical illness, psychological stress accentuates pathophysiological sequlae, through release of neuropeptides. The role of neuropeptides is suggested as an important field of investigation for critical care nursing. However, currently available data are insufficient to draw firm conclusions. Focussed studies on the physiologic correlates of psychological stress in the critically ill are needed. Relevance to clinical practice: If this hypothesis is corroborated, bedside quantification of selected neuropeptides may contribute to the assessment of stress and of the effectiveness of psychological support interventions in the future. Moreover, psychosocial and, probably, pharmacological support interventions may be effective adjuncts to the care of the critically ill.	en
heal.journalName	Nursing in Critical Care	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true