Modern fertility
preservation methods in female malignancy

dc.contributor.author	Ζαφειρίου, Σταμάτης	el
dc.contributor.author	Ζερβούδης, Στέφανος	el
dc.contributor.author	Οικονομίδης, Παναγιώτης	el
dc.contributor.author	Πολύζος, Δημήτριος	el
dc.contributor.author	Ιατράκης, Γεώργιος Μ.	el
dc.date.accessioned	2015-05-12T17:05:26Z
dc.date.available	2015-05-12T17:05:26Z
dc.date.issued	2015-05-12
dc.identifier.uri	http://hdl.handle.net/11400/10228
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://gineco.pulsmedia.ro/	en
dc.subject	Female malignancy
dc.subject	Ovarian tissue cryopreservation
dc.subject	Autotransplantation
dc.subject	xenotransplantation
dc.subject	In vitro ovarian maturation
dc.subject	Vitrification
dc.subject	Γυναικεία κακοήθεια
dc.subject	Κρυοσυντήρηση ωοθηκών ιστού
dc.subject	Αυτομεταμόσχευση
dc.subject	Ξενομεταμόσχευση
dc.subject	Ωρίμαση οωθηκών in vitro
dc.subject	Υαλοποίηση
dc.title	Modern fertility preservation methods in female malignancy	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Gynecology
heal.classification	Ιατρική
heal.classification	Γυναικολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85058092
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Γυναικολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85010471
heal.keywordURI	http://lod.nal.usda.gov/45415
heal.contributorName	Λυκερίδου, Κατερίνα	el
heal.language	en
heal.access	free
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Μαιευτικής	el
heal.publicationDate	2009
heal.bibliographicCitation	Zafeiriou, S., Zervoudis, S., Economides, P., Polyzos, D., Iatrakis, G., et al. (2009) Modern fertility preservation methods in female malignancy. In "Gineco.eu. Journal of Obstetrics and Gynecology", 5, p. 40-42. Available from: http://gineco.pulsmedia.ro/index.php/arhiv/38 [Accessed: 12/05/2015]	en
heal.abstract	Female malignancies can induce severe fertility issues in reproductive age women due to the therapeutic procedures addressing such malignancies (radiotherapy, chemotherapy, surgical intervention). Conservative treatment with medication, while allowing the ovarian tissue to remain intact (antioxidant regimens, gametogenesis- suspending regimens), does not seem to provide any clinical benefits. Ovarian tissue cryopreservation was recently developed in order to overcome the loss of viable follicles (due either to malignancy or to therapeutic side-effects) whenever patient’s clinical status permits it; the ovarian tissue is later thawed and used for patient’s fertility benefits. There are mainly three methods addressing this issue: autotransplantation (albeit orthotopic - in pelvis - or heterotopic), xenotransplantation (mainly in mice) and in vitro follicular maturation (IVM). The IVM of ovocytes (harvested either by follicular retrieval or by laparoscopic ovarian tissue biopsy) followed by modern rapid cryopreservation method (vitrification) seems to be the most promising method. Cryopreserved tissue is then restored and used (as soon as the clinical status permits it) for in vitro fertilization (IVF) and embryo transfer procedures.	en
heal.publisher	Vladareanue, Radu	en
heal.publisher	Navolan, Dan B.	en
heal.publisher	Badiu, Diana	en
heal.journalName	Gineco.eu. Journal of Obstetrics and Gynecology	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true