A pilot study investigating the minimum requirements necessary for grading astrocytomas remotely

dc.contributor.author	Γκλώτσος, Δημήτριος	el
dc.contributor.author	Γεωργιάδης, Παντελής	el
dc.contributor.author	Κωστόπουλος, Σπυρίδων	el
dc.contributor.author	Δασκαλάκης, Αντώνης	el
dc.contributor.author	Καλατζής, Ιωάννης	el
dc.date.accessioned	2015-05-14T11:25:55Z
dc.date.issued	2015-05-14
dc.identifier.uri	http://hdl.handle.net/11400/10358
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.ncbi.nlm.nih.gov/pubmed/20701092	en
dc.source	http://www.karger.com/Article/Abstract/325418	en
dc.subject	Astrocytomas
dc.subject	Histologic characteristics
dc.subject	Αστροκυτώματα
dc.subject	Ιστολογικά χαρακτηριστικά
dc.title	A pilot study investigating the minimum requirements necessary for grading astrocytomas remotely	en
heal.type	journalArticle
heal.classification	Technology
heal.classification	Biomedical engineering
heal.classification	Τεχνολογία
heal.classification	Βιοϊατρική τεχνολογία
heal.classificationURI	http://zbw.eu/stw/descriptor/10470-6
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85014237
heal.classificationURI	N/A-Τεχνολογία
heal.classificationURI	N/A-Βιοϊατρική τεχνολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh92001188
heal.contributorName	Ραβαζούλα, Παναγιώτα	el
heal.contributorName	Κάβουρας, Διονύσης Α.	el
heal.identifier.secondary	DOI:10.1159/000325418
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Τ.Ε.Ι. Αθήνας. Σχολή Τεχνολογικών Εφαρμογών. Τμήμα Μηχανικών Βιοϊατρικής Τεχνολογίας Τ.Ε.	el
heal.publicationDate	2009
heal.bibliographicCitation	Glotsos, D., Georgiadis, P., Kostopoulos, S., Daskalakis, A., Kalatzis, I., et al. (2009). A pilot study investigating the minimum requirements necessary for grading astrocytomas remotely. Analytical and Quantitative Cytology and Histology.31(5). pp. 262-268. Journal of Reproductive Medicine: 2009.	en
heal.abstract	OBJECTIVE: To investigate the minimum requirements necessary for remote grading astrocytomas in terms of selected static images and descriptive histologic characteristics. STUDY DESIGN: A histopathologist examined 106 formalin-fixed, paraffin-embedded tissue samples of low- and high-grade astrocytomas. Interobserver-checked cases were reviewed under a microscope to estimate the accuracy of the conventional glass slide diagnoses. Then cases based on 5 static-digitized images from each patient were diagnosed. Next, the grade of each tumor was assessed based on the set of 5 images and the World Health Organization (WHO) description of 8 histologic characteristics defined as crucial in grading astrocytomas. Finally, an evaluation was made using a custom-designed decision support system. RESULTS: Conventional glass slide diagnosis was 93.9%. Diagnosis based only on the set of 5 images dropped to 81.6%. Diagnosis based on the set of 5 images and the WHO characteristics boosted accuracy to 88.8%. Accuracy improved to 91.8% with the addition of the decision support system. CONCLUSION: Our findings suggest that a telepathology system might be valuable for accurate grade diagnosis of astrocytomas-providing a means for avoiding diagnostic errors-without blocks or slides having to leave the department. This could significantly reduce the overall time and cost of diagnosis.	en
heal.publisher	Journal of Reproductive Medicine	en
heal.journalName	Analytical and Quantitative Cytology and Histology	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false