Dosimetric characteristics of a new polymer gel and their dependence on post-preparation and post-irradiation time

dc.contributor.author	Παπουτσάκη, Μαριάνθη - Βασιλική	el
dc.contributor.author	Μαρής, Θωμάς Γ.	el
dc.contributor.author	Παππάς, Ευάγγελος	el
dc.contributor.author	Παπαδάκης, Αντώνιος Ε.	el
dc.contributor.author	Δαμηλάκης, Iωάννης	el
dc.date.accessioned	2015-05-17T17:20:20Z
dc.date.available	2015-05-17T17:20:20Z
dc.date.issued	2015-05-17
dc.identifier.uri	http://hdl.handle.net/11400/10605
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.sciencedirect.com/science/article/pii/S1120179713000045#?np=y	el
dc.subject	Radiotherapy
dc.subject	Magnetic resonance imaging
dc.subject	Normoxic polymer gel dosimetry
dc.subject	Ακτινοθεραπεία
dc.subject	Μαγνητική τομογραφία
dc.subject	Beam profile
dc.subject	Προφίλ δέσμης
dc.title	Dosimetric characteristics of a new polymer gel and their dependence on post-preparation and post-irradiation time	en
heal.type	journalArticle
heal.secondaryTitle	effect on X-ray beam profile measurements	en
heal.classification	Technology
heal.classification	Radiology, Medical
heal.classification	Τεχνολογία
heal.classification	Ακτινολογία, Ιατρική
heal.classificationURI	http://zbw.eu/stw/descriptor/10470-6
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85110777
heal.classificationURI	N/A-Τεχνολογία
heal.classificationURI	N/A-Ακτινολογία, Ιατρική
heal.keywordURI	http://zbw.eu/stw/descriptor/19529-3
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85079741
heal.identifier.secondary	doi:10.1016/j.ejmp.2013.01.003
heal.language	en
heal.access	campus
heal.recordProvider	Τ.Ε.Ι. Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ραδιολογίας και Ακτινολογίας.	el
heal.publicationDate	2013-09
heal.bibliographicCitation	Papoutsaki, Μ.-V., Maris, T. G., Pappas, E., Papadakis, A. E. and Damilakis, J. (2013). Dosimetric characteristics of a new polymer gel and their dependence on post-preparation and post-irradiation time: effect on X-ray beam profile measurements. "Physica Medica", 29(5), September 2013. pp. 453-460. Available from: http://www.sciencedirect.com/science/article/pii/S1120179713000045#. [Accessed 01/02/2013]	en
heal.abstract	The aim of this study is to dosimetrically characterize a new MRI based polymer gel system and to evaluate its usefulness in clinical practice just in terms of beam profile measurements. Normoxic N-vinylpyrrolidone based polymer gel (VIPET) phantoms were produced and used in order to perform three main sets of experiments: a) dose–response evaluation and reproducibility experiments, b) experiments for the evaluation of sensitivity of dose characteristics on ‘gel manufacture – irradiation’ time interval and c) experiments for the evaluation of sensitivity of dose characteristics on ‘irradiation – MRscanning’ time interval. It has been shown that this gel system can be used in a wide dose-range of 0–60 Gy. It exhibits a linear dose–response in the dose-range of 2–35 Gy. Following the proposed manufacturing method the dose–response characteristics are reproducible. Moreover, it seems that the optimum ‘gel manufacturing – irradiation’ time interval is 1 day. However, a ‘gel manufacturing – irradiation’ time interval up to ∼1 week can be safely used. The optimum ‘irradiation – MRscanning’ time interval in terms of dose–response sensitivity and dose resolution can be reliably ranged from 1 day to 3 weeks. Finally, X-ray beam profile gel-measurements were performed and found to be in satisfying agreement with corresponding small sensitive volume ion chamber measurements. VIPET gel dosimeters preserved the spatial integrity of the dose distribution during a time period of 50 days post-irradiation. The studied gel system can be safely used in clinical practice within the practical limitations found and described in this work.	en
heal.journalName	Physica Medica	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true