Nasal bone as an ultrasonographic marker for down syndrome

dc.contributor.author	Λυκερίδου - Αβραμιώτη, Κατερίνα	el
dc.contributor.author	Γουρουντή, Κλεάνθη	el
dc.contributor.author	Κούρτης, Πλούταρχος, Χ.	el
dc.date.accessioned	2015-05-19T15:40:45Z
dc.date.issued	2015-05-19
dc.identifier.uri	http://hdl.handle.net/11400/10739
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://pharmakonpress.gr/	el
dc.subject	Ultrasound
dc.subject	Fetal nasal bone
dc.subject	Down syndrome
dc.subject	Screening
dc.subject	Υπέρηχος
dc.subject	Ρινικό οστό εμβρύου
dc.subject	Σύνδρομο Down
dc.title	Nasal bone as an ultrasonographic marker for down syndrome	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Midwifery
heal.classification	Ιατρική
heal.classification	Μαιευτική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh96006072
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Μαιευτική
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85039232
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Μαιευτικής	el
heal.publicationDate	2004
heal.bibliographicCitation	Lykeridou, K., Gourounti, K. and Kourtis, P. (2004) Nasal bone as an ultrasonographic marker for down syndrome. "Epitheorese Klinikes Farmakologias kai Farmakokinetikes", 18 (3), p. 255-260. Available from: http://pharmakonpress.gr/?p=5723 [Accessed: 19/05/2015].	en
heal.abstract	The objective of this review article is to inform about the role of the ultrasonographic appearance of the fetal nasal bone in the prenatal screening for the diagnosis of the Down syndrome. During the pregnancy the identification of affected fetuses is dependent on sonographic markers, such as nuchal translucency, nuchal fold, pyelectasis, hyperechoic bowel, echogenic intracardiac foci. Today the appearance of the fetal nasal bone can be used as a new promising ultrasonographic marker for the Down syndrome during the pregnancy. Normally the fetal nasal bone is sonographically apparent at 11 weeks of gestation and the fetal nasal bone length increases with the increase of the crown-rump rump length of the fetus. The absence or the hypoplasia of a nasal bone is associated with a high risk for trisomy 21 and it is a highly sensitive and specific marker for this chromosomal abnormality. Recently the nasal bone has been shown to be absent in the majority of the fetuses with Down syndrome, compared with a small percentage of normal fetuses. Therefore a short or an absent nasal bone is associated with an increased likelihood ratio for fetal Down syndrome. The addition of the fetal nasal bone in the prenatal screening for the detection of the Down syndrome can increase the detection rate and decrease the false positive rate.	en
heal.publisher	Πλέσσα, Ελένη Σ.	el
heal.journalName	Epitheorese Klinikes Farmakologias kai Farmakokinetikes	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false