Negative correlations of serum total-homocysteine and HDL-c
levels in ICU patients

dc.contributor.author	Σαμαρά, Ιωάννα	el
dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.contributor.author	Καλκάνη, Ελένη	el
dc.contributor.author	Τζιμογιάννη, Αλεξάνδρα	el
dc.contributor.author	Μπουρνουσούζης, Νικόλαος	el
dc.contributor.author	Φύτου - Παλληκάρη, Αθηνά	el
dc.date.accessioned	2014-07-14T20:04:10Z
dc.date.available	2014-07-14T20:04:10Z
dc.date.issued	2014-07-14
dc.identifier.uri	http://hdl.handle.net/11400/1260
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	www.hsj.gr	en
dc.subject	cholesteryl ester transfer protein
dc.subject	High density lipoproteins
dc.subject	Low density lipoproteins
dc.subject	Triglycerides
dc.subject	Paraoxonase
dc.subject	Total serum Homocysteine (tHcy)
dc.subject	Paraoxonase-1 (PON1)
dc.title	Negative correlations of serum total-homocysteine and HDL-c levels in ICU patients	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Ιατρική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	N/A-Ιατρική
heal.keywordURI	http://lod.nal.usda.gov/146581
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85060667
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh89003534
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85137515
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2002008729
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Νοσηλευτικής	el
heal.publicationDate	2010-09
heal.bibliographicCitation	Samara, I., Karikas, G.A., Kalkani, E., Tzimogianni, A., Bournousouzis, N., Fytou-Pallikari., A.. (2010). Negative correlations of serum total-homocysteine and HDL-c levels in ICU patients. "Health Science Journal". 4 (3), 189-92.	en
heal.abstract	An elevated plasma level of total homocysteine (tHcy) has long been known as an independent predictor of cardiovascular disease (CVD). However, in the absence of a clear mechanism linking tHcy to CVD, there has been an ongoing debate whether this relationship is one of cause and effect or whether an elevated level of plasma tHcy is an epiphenomenon. The aim of the present study was to evaluate possible correlations between high levels of tHcy and the anti-inflammatory agent HDL-C along with the atherogenic LDL-C and TGs in adult patients with acute cardiovascular events. Method and Materials: tHcy, TGs, HDL-C and LDL-C levels were measured in 94 patients (51 men, 43 women) 48-66 y aged, who were admitted to ICU of Cardiology Department. tHcy levels were measured using fluorescence polarization immunoassay (FPIA). Results: Mean serum tHcy was found 16.63±7.55 μmol/l. There was no significant correlation between tHcy and TGs and LDL-C levels. On the contrary, a negative relationship between tHcy and HDL-C concentration was found with Pearson’s correlation coefficient (r = – 0.42). Conclusions: In this study, we detected and evaluated a negative relationship between t-Hcy and HDL-C levels in a hospitalized ICU population from the Greater Metropolitan area of Athens.	en
heal.publisher	Μαρβάκη, Χριστίνα	el
heal.journalName	Health Science Journal	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true
heal.dateCreated	2010-07