Chemoprevention molecular and biochemical mechanisms involved in cancer control and management

dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.date.accessioned	2014-07-15T00:41:57Z
dc.date.available	2014-07-15T00:41:57Z
dc.date.issued	2014-07-15
dc.identifier.uri	http://hdl.handle.net/11400/1288
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	www.hsj.gr	en
dc.subject	Cancer--Chemoprevention
dc.subject	epigenetics
dc.subject	Phytochemicals
dc.subject	Polyphenols
dc.subject	Drugs--Prescribing--Law and legislation
dc.subject	Epigenetic mechanisms
dc.title	Chemoprevention molecular and biochemical mechanisms involved in cancer control and management	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Ιατρική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	N/A-Ιατρική
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh92002505
heal.keywordURI	http://lod.nal.usda.gov/37589
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh99001233
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh88004563
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2003005269
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Νοσηλευτικής	el
heal.publicationDate	2011-06
heal.bibliographicCitation	Karikas, G.A.. (2010). Chemoprevention molecular and biochemical mechanisms involved in cancer control and management. "Health Science Journal". 5 (2), 149-56.	en
heal.abstract	Background: Cancer is a growing health problem around the world. Throughout history, natural products have been the most significant source of anticancer and chemopreventing agents. More than 1,000 different phytochemicals are already proved to possess interesting chemopreventing activities. Aim: To present a number of recent biochemical and molecular mechanisms, in relation to natural and synthetic chemopreventing substances for cancer control and management.Results: Vegetables and fruit are excellent sources of cancer-preventive substances. Natural products consist of a wide variety of biologically active phytochemicals including phenolics, flavonoids, carotenoids, etc. have been shown to suppress early and late stages of carcinogenesis. Effectiveness of chemopreventive agents reflects their ability to counteract certain upstream signals, such as NF-kB, β-catenin, etc. Furthermore, epigenetic modified agents, alone or in combination with conventional anticancer drugs may prove to be a significant advance over the conventional anticancer control. Conclusion: Chemoprevention by edible phytochemicals is nowadays considered to be an inexpensive, readily applicable, and accessible approach to cancer control and management. In addition, the promotion of awareness and consumption of phytochemicals as a cancer-preventive strategy would be cost-effective, within the health system.	en
heal.publisher	Μαρβάκη, Χριστίνα	el
heal.journalName	Health Science Journal	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true
heal.dateCreated	2011-04