Effects of exercise training on skeletal muscle fiber type distribution in chronic heart failure patients

dc.contributor.author	Τζάνης, Γεώργιος	el
dc.contributor.author	Δημόπουλος, Σταύρος	el
dc.contributor.author	Καρατζάνος, Ελευθέριος	el
dc.contributor.author	Τασούλης, Αθανάσιος	el
dc.contributor.author	Τερροβίτης, Ιωάννης	el
dc.date.accessioned	2014-07-20T19:16:18Z
dc.date.available	2014-07-20T19:16:18Z
dc.date.issued	2014-07-20
dc.identifier.uri	http://hdl.handle.net/11400/1484
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	www.hsj.gr	en
dc.subject	Muscles--Diseases
dc.subject	sclereids
dc.subject	exercise test
dc.subject	Continuous training (Exercise)
dc.subject	Interval training
dc.subject	strength training
dc.subject	Άσκηση
dc.subject	Φυσική αγωγή
dc.subject	Μυοπάθεια
dc.subject	Προπόνηση
dc.subject	Τεστ κοπώσεως
dc.title	Effects of exercise training on skeletal muscle fiber type distribution in chronic heart failure patients	en
heal.type	journalArticle
heal.generalDescription	Research article	en
heal.classification	Medicine
heal.classification	Internal medicine
heal.classification	Cardiology
heal.classification	Physical exercise and training
heal.classification	Ιατρική
heal.classification	Καρδιολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85067347
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85020214
heal.classificationURI	N/A-Physical exercise and training
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Καρδιολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85088688
heal.keywordURI	http://lod.nal.usda.gov/62611
heal.keywordURI	http://lod.nal.usda.gov/12222
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2010009650
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2010009475
heal.keywordURI	http://lod.nal.usda.gov/13601
heal.contributorName	Ροντογιάννη, Δήμητρα	el
heal.contributorName	Νανάς, Σεραφείμ Ν.	el
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Νοσηλευτικής	el
heal.publicationDate	2014-01
heal.bibliographicCitation	Tzanis, G., Dimopoulos, S., Karatzanos, E. & Tasoulis, A. (January 2014). Effects of exercise training on skeletal muscle fiber type distribution in chronic heart failure patients. “Health Science Journal”. 8(1):116-125.	en
heal.abstract	Background: Patients with heart failure (HF) are characterized by several skeletal muscle abnormalities that are closely related to their exercise intolerance. Aim of this study was to investigate the effects of three different interval exercise training programs on skeletal muscle fiber-type distribution and aerobic capacity of HF patients. Method and Material: The study consisted of 10 HF patients that participated in a rehabilitation program 3 times per week, for a total of 36 sessions. Patients performed cardiopulmonary exercise test (CPET) and percutaneous needle biopsy of the vastus lateralis muscle before and after the completion of the program. Histological measurements included the fiber type distribution and cross section area (CSA) of skeletal muscle fiber. Main CPET measurements included oxygen uptake at peak (VO2p), at anaerobic threshold (AT), peak work (WRp) and the slope of ventilatory equivalent for carbon dioxide output (VE/VCO2slope). Results: After the exercise training program there was a significant increase in the CSA of type I (4509±1184 to 4862±1154 μm2, p<0.001) and type II (from 4408±1166 to 4937±1160 μm2, p<0.001) fibers. The proportion of aerobic type I fibers increased significantly from 43±11 to 51±6% (p=0.05). The percentage change of type I CSA was significantly correlated with the percentage change of WRp (r=0.814, p=0.004). WRp, VO2p, AT increased significantly (108±36 to 129±49 watts, p=0.008; 17.7±4.2 to 19.7±4.6 ml/kg/min, p=0.024; 12.0±3.3 to 13.5±4.1 ml/kg/min, p=0.05, respectively) and VE/VCO2slope decreased (35.1±8.0 to 31.3±5.7, p=0.045). Conclusions: The results indicate that interval exercise training might have an anabolic effect by increasing the CSA of muscle fibers and could improve aerobic capacity probably by inducing a reshift of fiber type distribution in HF patients.	en
heal.publisher	Μαρβάκη, Χριστίνα	el
heal.journalName	Health Science Journal	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true