Risk factors and attributable mortality of carbapenem-resistant acinetobacter baumannii infections

dc.contributor.author	Αποστολοπούλου, Ελένη	el
dc.contributor.author	Ραφτόπουλος, Βασίλειος	el
dc.contributor.author	Ζαρκάδας, Προκόπης	el
dc.contributor.author	Τόσκα, Αικατερίνη	el
dc.contributor.author	Βελδέκης, Δημήτριος	el
dc.date.accessioned	2014-07-20T19:25:33Z
dc.date.available	2014-07-20T19:25:33Z
dc.date.issued	2014-07-20
dc.identifier.uri	http://hdl.handle.net/11400/1485
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	www.hsj.gr	en
dc.subject	Acinetobacter baumannii
dc.subject	carbapenems
dc.subject	cross infection
dc.subject	Intensive care units
dc.subject	Νοσοκομειακή λοίμωξη
dc.subject	Θνησιμότητα
dc.subject	Εντατική θεραπεία
dc.subject	Carbapenem resistance
dc.subject	Mortality
dc.title	Risk factors and attributable mortality of carbapenem-resistant acinetobacter baumannii infections	en
heal.type	journalArticle
heal.generalDescription	Research article	en
heal.classification	Medicine
heal.classification	Ιατρική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	N/A-Ιατρική
heal.keywordURI	http://lod.nal.usda.gov/2902
heal.keywordURI	http://lod.nal.usda.gov/148699
heal.keywordURI	http://lod.nal.usda.gov/147765
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85067186
heal.contributorName	Τσιλίδης, Κωνσταντίνος	el
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Νοσηλευτικής	el
heal.publicationDate	2014-01
heal.bibliographicCitation	Tzanis, G., Dimopoulos, S., Karatzanos, E. & Tasoulis, A. (January 2014). Effects of exercise training on skeletal muscle fiber type distribution in chronic heart failure patients. “Health Science Journal”. 8(1):116-125.	en
heal.abstract	Background: The incidence density, the risk factors and the attributable mortality of carbapenem-resistant Acinetobacter baumannii (CR-AB) infections are rarely investigated. Aim: The aim of the present study was to determine the risk factors for CR-AB infection and to investigate whether CR-AB infection significantly increases the 28-day ICU mortality rate. Methods: A matched case-control study was conducted at the Medical/Surgical intensive care unit (ICU) of “SOTIRIA” general hospital in Athens, Greece from January 2009 to March 2010. Out of 156 ICU-admitted patients, 50 case-control pairs were selected. Cases were patients who acquired microbiologically documented CR-AB infection, while control patients without A. baumannii infection and were matched to the cases on APACHE II score, age, and length of ICU stay. Results: The incidence density of CR-AB infections was 16.8 /1000 ICU days. Multivariate conditional logistic regression analysis showed that the previous exposure to more than three different antibiotic classes was the only independent risk factor for the development of CR-AB (OR=34.0, 95% CI=2.22-522, P=0.01). The 28-day ICU mortality rates for cases and controls were 54% and 52%, respectively. Thus, the crude attributable mortality for CR-AB infections was 0.02 (95% CI=-0.18-0.22, P=0.84). Multivariate logistic regression analysis showed that CR-AB infection was not an independent predictor for 28-day ICU mortality rate (OR=1.40, 95% CI=0.46-4.22,P=0.55). Conclusions: Previous exposure to more than three different antibiotic classes was independently and significantly associated with the development of CR-AB. CR-AB infection was not associated with 28-day ICU mortality.	en
heal.publisher	Μαρβάκη, Χριστίνα	el
heal.journalName	Health Science Journal	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true