Molecular nanomedicine towards cancer

dc.contributor.author	Ψημαδάς, Δημήτριος	el
dc.contributor.author	Γεωργούλιας, Παναγιώτης	el
dc.contributor.author	Βαλοτάσσιου, Βαρβάρα	el
dc.contributor.author	Λούντος, Γεώργιος	el
dc.date.accessioned	2015-06-05T22:24:59Z
dc.date.available	2015-06-05T22:24:59Z
dc.date.issued	2015-06-06
dc.identifier.uri	http://hdl.handle.net/11400/15240
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1520-6017	en
dc.subject	Distribution
dc.subject	Imaging methods
dc.subject	Liposomes
dc.subject	Micelles
dc.subject	Nanoparticles
dc.subject	Διανομή
dc.subject	Απεικονιστικές μέθοδοι
dc.subject	Λιποσώματα
dc.subject	Μικύλλια
dc.subject	Νανοσωματίδια
dc.title	Molecular nanomedicine towards cancer	en
heal.type	journalArticle
heal.secondaryTitle	111In-labeled nanoparticles	en
heal.classification	Medicine
heal.classification	Oncology
heal.classification	Ιατρική
heal.classification	Ογκολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unesco6/320713
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Ογκολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85077311
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85084678
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85089689
heal.identifier.secondary	DOI: 10.1002/jps.23146
heal.language	en
heal.access	campus
heal.recordProvider	Σχολή Τεχνολογικών Εφαρμογών. Τμήμα Μηχανικών Βιοϊατρικής Τεχνολογίας Τ.Ε.	el
heal.publicationDate	2012-07
heal.bibliographicCitation	Psimadas, D., Georgoulias, P., Valotassiou, V. and Loudos, G. (2012) Molecular nanomedicine towards cancer: 111In-labeled nanoparticles. "Journal of Pharmaceutical Sciences", 101 (7), p. 2271 - 2280. Available from: http://onlinelibrary.wiley.com/doi/10.1002/jps.23146/abstract [Accessed: 05/06/2015].	en
heal.abstract	Nanomedicine is the medical application of materials, devices, or systems in the nanometer scale and is currently undergoing explosive development. Molecular imaging of cancer using nanosized materials comprises an important part in diagnosis, therapy, and drug discovery in medical nanosciences. Radiopharmaceuticals are a key tool of molecular imaging in the field of nuclear medicine. The in vivo administration of radiolabeled nanoparticles (NPs) can provide an accurate biodistribution profile of the nanoformulations, as well as visualization of their route in vivo. Surface modifications of NPs with antibodies, peptides, or other small molecules that bind to tumor cell receptors have resulted in the development of sensitive and specific targeted imaging and diagnostic modalities for in vitro and in vivo applications. Radiometals are the most favorable of all radionuclides for labeling applications and they have the most suitable properties for single-photon emission computed tomography imaging. Indium-111 (111In), specifically, is a readily available gamma-emitting radiometal, which is widely used in clinical practice for diagnosis and/or therapy. Herein, we will overview the latest evolvement on 111In-labeled nanoparticles for biodistribution assessment and/or imaging evaluation of nanocarriers, as well as therapy in cancer.	en
heal.publisher	Borchardt, Ronald T.	en
heal.journalName	Journal of Pharmaceutical Sciences	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true