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dc.contributor.author Τσινισιζέλη, Νικολέτα el
dc.contributor.author Σωτηρούδης, Γεώργιος el
dc.contributor.author Ξενάκης, Αριστοτέλης el
dc.contributor.author Λυκερίδου - Αβραμιώτη, Κατερίνα el
dc.date.accessioned 2015-06-07T06:29:29Z
dc.date.available 2015-06-07T06:29:29Z
dc.date.issued 2015-06-07
dc.identifier.uri http://hdl.handle.net/11400/15385
dc.rights Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.source http://www.sciencedirect.com/science/article/pii/S0045653514011801 en
dc.subject Meconium
dc.subject Tobacco
dc.subject Μηκώνιο
dc.subject Καπνός
dc.title Determination of nicotine and cotinine in meconium from Greek neonates and correlation with birth weight and gestational age at birth en
heal.type journalArticle
heal.classification Medicine
heal.classification Midwifery
heal.classification Ιατρική
heal.classification Μαιευτική
heal.classificationURI http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI http://id.loc.gov/authorities/subjects/sh96006072
heal.classificationURI **N/A**-Ιατρική
heal.classificationURI **N/A**-Μαιευτική
heal.keywordURI http://id.loc.gov/authorities/subjects/sh85082793
heal.identifier.secondary doi:10.1016/j.chemosphere.2014.09.094
heal.language en
heal.access campus
heal.recordProvider Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Μαιευτικής. el
heal.publicationDate 2015-01
heal.bibliographicCitation Tsinisizeli, N., Sotiroudis, G., Xenakis, A. and Lykeridou-Avramioti, K. (January 2015). Determination of nicotine and cotinine in meconium from Greek neonates and correlation with birth weight and gestational age at birth. Chemosphere. 119. pp. 1200-1207. Elsevier Ltd: 2015. Available from: http://www.sciencedirect.com/science/article/pii/S0045653514011801 [Accessed 01/11/2014] el
heal.abstract Tobacco exposure during pregnancy is a major factor of morbidity and mortality for both the pregnant woman and the fetus. Several studies in the past have detected and quantified tobacco smoke biomarkers in infant meconium samples. Aim of this study was to measure prenatal exposure to tobacco smoke by detecting nicotine and cotinine in meconium and to try to evaluate the extent of exposure to smoke through passive smoking as well as the relationship between tobacco biomarker meconium concentrations and neonatal outcomes. Tobacco smoke biomarkers nicotine and cotinine were detected and quantitated in meconium from tobacco exposed and non-exposed Greek neonates using liquid chromatography–tandem mass spectrometry. The study included 45 neonates from active, passive and non-smoking women during pregnancy. The results showed significant values of nicotine and cotinine concentration in neonates from both active and passive smokers which reached 125 ng g−1 for nicotine and 98.5 ng g−1 for cotinine and varied according to the type and level of exposure. In general nicotine and cotinine concentrations correlated with the degree of active smoking by the mother. Similarly, nicotine and cotinine were measured in the meconium of infants of passive smokers at concentrations comparable to those of infants whose mothers were moderate smokers. Our findings show that exposure of the fetus to tobacco biomarkers can be substantial even in passive maternal smoking and there is a statistically significant negative correlation between nicotine or cotinine concentrations in meconium and birth weight or gestational age at birth. en
heal.publisher Elsevier Ltd en
heal.journalName Chemosphere en
heal.journalType peer-reviewed
heal.fullTextAvailability true


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Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες Except where otherwise noted, this item's license is described as Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες