A new bifunctional tridentate NSN ligand leading to cationic tricarbonyl fac-[M(NSN)(CO)3]+ (M = Re, 99mTc) complexes

dc.contributor.author	Μυλωνάς, Ιωακείμ	el
dc.contributor.author	Τριάντης, Χαράλαμπος	el
dc.contributor.author	Παναγιωτοπούλου, Αγγελική	el
dc.contributor.author	Πάτσης, Γεώργιος Π.	el
dc.contributor.author	Ραφτοπούλου, Αικατερίνη Π.	el
dc.date.accessioned	2015-06-07T20:19:39Z
dc.date.available	2015-06-07T20:19:39Z
dc.date.issued	2015-06-07
dc.identifier.uri	http://hdl.handle.net/11400/15546
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.elsevier.com/	en
dc.subject	Bifunctional
dc.subject	Rhenium
dc.subject	Technetium
dc.subject	Tricarbonyl complexes
dc.subject	τρικαρβονυλικά συμπλέγματα
dc.title	A new bifunctional tridentate NSN ligand leading to cationic tricarbonyl fac-[M(NSN)(CO)3]+ (M = Re, 99mTc) complexes	en
heal.type	journalArticle
heal.classification	Technology
heal.classification	Electrical engineering
heal.classification	Τεχνολογία
heal.classification	Ηλεκτρολογία Μηχανολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85133147
heal.classificationURI	http://zbw.eu/stw/descriptor/18426-4
heal.classificationURI	N/A-Τεχνολογία
heal.classificationURI	N/A-Ηλεκτρολογία Μηχανολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85133086
heal.contributorName	Τερζής, Αριστείδης	el
heal.contributorName	Ψυχάρης, Βασίλειος	el
heal.contributorName	Κομιώτης, Δημήτριος	el
heal.contributorName	Πελεκάνου, Μαρία	el
heal.contributorName	Πιρμέττης, Ιωάννης Χ.	el
heal.contributorName	Παπαδόπουλος, Μηνάς Σ.	el
heal.identifier.secondary	DOI: 10.1016/j.ica.2013.02.001
heal.language	en
heal.access	campus
heal.publicationDate	2013-05-01
heal.bibliographicCitation	MILONAS, I., TRIANTIS, C., PANAGIOTOPOULOU, A., PATSIS, G.P., RAFTOPOULOU, A.P., et al. (2013). A new bifunctional tridentate NSN ligand leading to cationic tricarbonyl fac-[M(NSN)(CO)3]+ (M = Re, 99mTc) complexes. Inorganica Chimica Acta. [online] 400. p. 2-6. Available from: http://www.elsevier.com/[Accessed 09/02/2013]	en
heal.abstract	The synthesis and characterization of the new NSN tridentate bifunctional chelating agent 3-[2-(2′-pyridin-2-yl-ethylsulfanyl)ethylamino] propionic acid (as its hydrochloric salt, 1) and of its corresponding rhenium complex fac-[Re(NSN)(CO)3]+, 2, is described. Both compounds were characterized by elemental analysis, IR and NMR spectroscopies and X-ray crystallography. In complex 2 the coordination geometry around rhenium is distorted octahedral with the NSN atoms participating in the coordination sphere while the carboxylate group remains free. At tracer level, the analogous complex fac-[99mTc(NSN)(CO)3]+, 3, was obtained in high yield by reacting ligand 1 with the fac-[99mTc(H 2O)3(CO)3]+ precursor at pH 6.5. The structure of 3 was established by HPLC comparison to the prototype rhenium complex 2. Complex 3 is stable in solution as well as in the presence of strongly coordinating agents like histidine or cysteine. Our data indicate that ligand 1 can be used as a bifunctional NSN chelating agent in the design of potential 99mTc-radiopharmaceuticals.	en
heal.publisher	Elsevier	en
heal.journalName	Inorganica Chimica Acta	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true