Benzimidazole derivatives as NSO ligands for the fac-[M(CO) 3]+ (M = Re, 99mTc)

dc.contributor.author	Τσοτάκος, Θεόδωρος	el
dc.contributor.author	Τσουκαλάς, Χαράλαμπος	el
dc.contributor.author	Πάτσης, Γεώργιος Π.	el
dc.contributor.author	Παναγιωτοπούλου, Αγγελική	el
dc.contributor.author	Nikolić, Nadežda S.	en
dc.date.accessioned	2015-06-07T20:42:27Z
dc.date.available	2015-06-07T20:42:27Z
dc.date.issued	2015-06-07
dc.identifier.uri	http://hdl.handle.net/11400/15552
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.elsevier.com/	en
dc.subject	Fatty acid
dc.subject	Rhenium
dc.subject	Technetium-99m
dc.subject	Tricarbonyl
dc.subject	Τρικαρβονυλικό
dc.subject	Λιπαρό οξύ
dc.subject	Ρήνειο
dc.title	Benzimidazole derivatives as NSO ligands for the fac-[M(CO) 3]+ (M = Re, 99mTc)	en
heal.type	journalArticle
heal.classification	Technology
heal.classification	Chemical technology
heal.classification	Τεχνολογία
heal.classification	Χημική τεχνολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85133147
heal.classificationURI	http://skos.um.es/unescothes/C00565
heal.classificationURI	N/A-Τεχνολογία
heal.classificationURI	N/A-Χημική τεχνολογία
heal.contributorName	Janković, Drina V.	en
heal.contributorName	Djokić, D.	en
heal.contributorName	Ραφτοπούλου, Αικατερίνη Π.	el
heal.contributorName	Τερζής, Αριστείδης	el
heal.contributorName	Παπαγιαννοπούλου, Διονυσία	el
heal.contributorName	Πελεκάνου, Μαρία	el
heal.contributorName	Παπαδόπουλος, Μηνάς Σ.	el
heal.contributorName	Πιρμέττης, Ιωάννης Χ.	el
heal.identifier.secondary	DOI: 10.1016/j.ica.2011.07.035
heal.language	en
heal.access	campus
heal.publicationDate	2011-11-01
heal.bibliographicCitation	TSOTAKOS, T., TSOUKALAS, C., PATSIS, G.P., PANAGIOTOPOULOU, A.,NICOLIC, N.S., et al. (2011). Benzimidazole derivatives as NSO ligands for the fac-[M(CO) 3]+ (M = Re, 99mTc). Inorganica Chimica Acta. [online] 377 (1). p. 62-68. Available from: http://www.elsevier.com/[Accessed 05/08/2011]	en
heal.abstract	Two rhenium(I) tricarbonyl complexes with the tridentate monoanionic NSO ligands, 4-(benzimidazol-2-yl)-3-thiabutanoic acid (complex 3) and [1-(11-carboxyundecanyl)-4-(benzimidazol-2-yl)]-3-thiabutanoic acid (complex 4) were synthesized and characterized by spectroscopic methods and elemental analysis. X-ray crystallographic analysis of complex 3 revealed a distorted octahedral geometry around rhenium defined by the three facially bound CO groups and the NSO donor atom set of the tridentate ligand. The analogous technetium-99m complexes (complexes 5 and 6) were also prepared quantitatively by reaction of the NSO ligands with the fac-[99mTc(H 2O)3(CO)3]+ synthon and their identity was established by chromatographic comparison to their rhenium congeners. Biodistribution in mice of complex 6 bearing the fatty acid chain showed significant heart uptake (6.26 ± 0.79% ID/g p.i.) at 1 min accompanied, however, with a heart:blood ratio below 1.	en
heal.publisher	Elsevier	en
heal.journalName	Inorganica Chimica Acta	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true