Interaction of Salicylates and the other nonsteroidal anti-inflammatory agents with breast cancer endocrine treatment

dc.contributor.author	Ευγενία, Κ.Υ.	el
dc.date.accessioned	2015-06-07T23:05:56Z
dc.date.available	2015-06-07T23:05:56Z
dc.date.issued	2015-06-08
dc.identifier.uri	http://hdl.handle.net/11400/15604
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.scopus.com/record/display.url?origin=recordpage&eid=2-s2.0-84916917661&citeCnt=0&noHighlight=false&sort=plf-f&src=s&nlo=1&nlr=20&nls=&affilName=technological+educational+institute+of+athens&sid=AD00820B4B67BB0C9FBC05FFC31F57EA.CnvicAmOODVwpVrjSeqQ%3a70&sot=aff&sdt=cl&cluster=scopubyr%2c%222014%22%2ct&sl=61&s=%28AF-ID%28%22Technologiko+Ekpaideutiko+Idrima++Athinas%22+60002861%29%29&relpos=5	en
dc.subject	σαλικυλικά
dc.subject	καρκίνος του μαστού
dc.subject	ταμοξιφαίνη
dc.subject	συνεργιστική αλληλεπίδραση
dc.subject	Salicylates
dc.subject	breast cancer
dc.subject	Tamoxifen
dc.subject	synergistic interaction
dc.title	Interaction of Salicylates and the other nonsteroidal anti-inflammatory agents with breast cancer endocrine treatment	en
heal.type	journalArticle
heal.secondaryTitle	systematic review	en
heal.classification	Ογκολογία
heal.classification	Καρκίνος
heal.classification	Oncology
heal.classification	Cancer
heal.classificationURI	N/A-Ογκολογία
heal.classificationURI	N/A-Καρκίνος
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85094724
heal.classificationURI	http://zbw.eu/stw/descriptor/18899-3
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85116753
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85132219
heal.identifier.secondary	DOI: 10.1097/COC.0000000000000166
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2014-12-10
heal.bibliographicCitation	Eugenia, C.Y (2014) Interaction of Salicylates and the Other Nonsteroidal Anti-Inflammatory Agents With Breast Cancer Endocrine Treatment: Systematic Review. American Journal of Clinical Oncology: Cancer Clinical Trials. [Online] Available from: http://www.scopus.com [Accessed 07/06/2015]	en
heal.abstract	Despite advances in breast cancer treatment, mortality from breast cancer is still high. Undoubtedly, novel treatment strategies are needed for chemoprevention of high-risk women and for the treatment of receptor-negative breast cancer. An appealing strategy would be the combination of breast endocrine treatment with salicylates and the other nonsteroidal anti-inflammatory agents (NSAIDs). This systematic review aimed to synthesize evidence on the possible synergistic antitumor effect of breast cancer endocrine treatment with salicylates and the other NSAIDs. Electronic databases were searched with the appropriate search terms. Most of the identified studies investigated the possible synergistic effect of exemestane with celecoxib in different clinical settings including metastatic treatment, adjuvant treatment, ductal carcinoma in situ. The possible synergistic effect of tamoxifen with celecoxib was investigated in one experimental study and the possible synergistic effect of exemestane with aspirin was investigated in another experimental study. Synergistic effect was detected in the majority of the studies. In conclusion, existing limited evidence suggests synergistic interaction of salicylates and the other NSAIDs in the treatment of estrogen responsive breast cancer with clinical implications in the reversal of acquired resistance to breast cancer endocrine treatment and in chemoprophylaxis.	en
heal.publisher	Lippincott Williams and Wilkins	en
heal.journalName	American Journal of Clinical Oncology: Cancer Clinical Trials	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true