Show simple item record

dc.contributor.author Σπύρου, Σπυρίδων el
dc.contributor.author Λούντος, Γιώργος el
dc.date.accessioned 2015-06-18T00:43:22Z
dc.date.available 2015-06-18T00:43:22Z
dc.date.issued 2015-06-18
dc.identifier.uri http://hdl.handle.net/11400/16359
dc.rights Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.source http://www.sciencedirect.com en
dc.subject Ραδιολογία
dc.subject Radiology
dc.subject Προστάτης
dc.subject Δοσομετρία
dc.title Systematic investigation of the dosimetric effect of beam angles in IMRT of the prostate en
heal.type journalArticle
heal.classification Technology
heal.classification Medicine
heal.classification Τεχνολογία
heal.classification Ιατρική
heal.classificationURI http://id.loc.gov/authorities/subjects/sh85133147
heal.classificationURI http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI **N/A**-Τεχνολογία
heal.classificationURI **N/A**-Ιατρική
heal.identifier.secondary doi:10.1016/j.ejmp.2014.07.245
heal.language en
heal.access campus
heal.publicationDate 2014
heal.bibliographicCitation Spirou, S. and Loudos, G. (2014) Systematic investigation of the dosimetric effect of beam angles in IMRT of the prostate. "Physica Medica", 30 (1), p.85 en
heal.abstract Purpose: To systematically investigate how the choice of beam angles in IMRT of the prostate affects the dosimetry of the PTV and each OAR, as well as how the dosimetry of each structure is correlated with that of other structures. Methods and Materials: Five prostate patients, previously treated with a 5-beam IMRT plan to 86.4 Gy, were selected for this study. Candidate beams were defined in a 360° arc around the isocenter. Treatment plans were generated for each set of 5 beams taken out from the set of the candidate beams. First, all the optimization constraints, as well as all other algorithmic parameters, were kept fixed as in the clinical plan. Subsequently, additional constraints were placed on the rectum and bladder, in order to bring forth any differences between the beam sets. Preliminary Results: The methodology described previously has been manually applied to a single prostate patient for 9 candidate beams, equally spaced every 40°. Altogether 252 (126 x 2) plans were generated for this patient. All plans were normalized so that the maximum dose to the rectal wall is 99%. The envelope DVHs describe all the DVHs obtained from the 126 plans (Fig. 1). The clinical DVHs may or may not lie within the envelope because the clinical beam arrangement was not among the 126 examined. The envelope DVHs for the PTV is fairly narrow, indicating that coverage was not an issue for this patient, regardless of the beam arrangement used. However, the envelope DVHs for the rectum, bladder and, especially, the large bowel are much wider, suggesting that the choice of beam directions may have a significant impact on the treatment plan. The use of additional constraints improves the range of DVHs for the rectum, bladder and, especially, the large bowel. Conclusion: The choice of beam directions may have a significant impact on the dosimetry of the rectum, bladder and, especially, large bowel. Furthermore, the use of additional constraints has the potential to improve current treatment plans. These may, in turn, affect the patient’s quality of life and post-treatment disease management. en
heal.publisher Elsevier en
heal.journalName Physica Medica en
heal.journalType peer-reviewed
heal.fullTextAvailability true


Files in this item

  • Name: 1-s2.0-S1120179714004098-main.pdf
    Size: 189.5Kb
    Format: PDF

The following license files are associated with this item:

Show simple item record

Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες Except where otherwise noted, this item's license is described as Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες