Effect of mite-impermeable mattress encasings and an educational package
on the development of allergies in a multinational randomized, controlled
birth-cohort study – 24 months results of the Study of Prevention of Allergy
in Children in Europe

dc.contributor.author	Horak, F.	en
dc.contributor.author	Matthew, S.	en
dc.contributor.author	Ihorst, G.	en
dc.contributor.author	Arshad, Hassan	en
dc.contributor.author	Frischer, Thomas	en
dc.date.accessioned	2015-01-11T19:25:03Z
dc.date.available	2015-01-11T19:25:03Z
dc.date.issued	2015-01-11
dc.identifier.uri	http://hdl.handle.net/11400/3788
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	dust mites
dc.subject	Newborn infants
dc.subject	Primary prevention
dc.subject	Ακάρεα της οικιακής σκόνης
dc.subject	Νεογέννητα
dc.subject	Πρωτογενής πρόληψη
dc.title	Effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlled birth-cohort study – 24 months results of the Study of Prevention of Allergy in Children in Europe	en
heal.type	journalArticle
heal.generalDescription	And the SPACE study group	en
heal.classification	Medicine
heal.classification	Allergy
heal.classification	Ιατρική
heal.classification	Αλλεργία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85003662
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Αλλεργία
heal.keywordURI	http://lod.nal.usda.gov/32479
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85066048
heal.contributorName	Kuehr, Joachim	en
heal.contributorName	Schwieger, A.	en
heal.contributorName	Forster, J.	en
heal.identifier.secondary	Doi:10.1111/j.1365-2222.2004.02024.x
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας.Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Yγιεινής).	el
heal.publicationDate	2004
heal.bibliographicCitation	Horak, F., Matthews, S., Ihorst, G., Arshad, H., Frischer, T., et al. (2004) Effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlledbirth-cohort study – 24 months results of the Study of Prevention of Allergy in Children in Europe. "Clinical and Experimental Allergy". 34(8). p.1220-1225.	en
heal.abstract	Background Sensitization to house dust mite (HDM) is an important risk factor for the development of asthma and allergic disease in childhood. Higher levels of HDM allergen are linked to increased sensitization to HDM. Objective To study the effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a newborn cohort. Methods Six hundred and ninety-six newborns at high risk of developing allergies were enrolled in three European countries (Germany, Austria, UK) in a prospective, randomized, controlled birthcohort study. Children were randomly assigned to an intervention and control group. Intervention measures included the use of mite-impermeable mattress encasings for the child’s bed and a simple educational package on allergen avoidance. The control group received basic information about allergies. Children were followed up at age 6, 12, 18 and 24 months. Results 80.9% of the children were followed up to the age of 24 months. No difference in the prevalence of sensitization to HDM (control vs. intervention group: 8.4% vs. 6.1%, P50.33) or the development of symptoms (recurrent wheezing 10.3% vs. 10.7%, nocturnal cough 12.5% vs. 12.5%) or allergic diseases (asthma 3.5% vs. 5.1%, eczema 20.0% vs. 19.6%, rhinitis 28.9% vs. 25.8%) could be found between the control and intervention group. Conclusion In this study, HDM avoidance did not show a protective effect on the development of sensitization to HDM or symptomatic allergy in children at age 24 months.	en
heal.publisher	Blackwell Publishing Ltd	en
heal.journalName	Clinical and Experimental Allergy	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true