Assessment of levels of organochlorine
pesticides and their metabolites in the hair
of a Greek rural human population

dc.contributor.author	Τσατσάκης, Αριστείδης Μ.	el
dc.contributor.author	Τζατζαράκης, Εμμανουήλ Ν.	el
dc.contributor.author	Τουτουδάκη, Μαρία	el
dc.contributor.author	Μπαμπάτσικου, Φωτούλα Π.	el
dc.contributor.author	Αγγελάκης Ανδρέας Ν.	el
dc.date.accessioned	2015-01-12T00:13:03Z
dc.date.issued	2015-01-12
dc.identifier.uri	http://hdl.handle.net/11400/3795
dc.rights	An error occurred on the license name.	*
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	An error occurred getting the license - uri.	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://het.sagepub.com/	en
dc.subject	Organochlorine compounds
dc.subject	Metabolites
dc.subject	human population
dc.subject	public health
dc.subject	Οργανοχλωρίνες
dc.subject	Μεταβολίτης
dc.subject	Ανθρώπινος πληθυσμός
dc.subject	Δημόσια υγεία
dc.title	Assessment of levels of organochlorine pesticides and their metabolites in the hair of a Greek rural human population	en
heal.type	journalArticle
heal.classification	Toxicology, Experimental
heal.classification	Pesticides--Toxicology
heal.classification	Τοξικολογία
heal.classification	Φυτοφάρμακα Τοξικολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85136332
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85100285
heal.classificationURI	N/A-Τοξικολογία
heal.classificationURI	N/A-Φυτοφάρμακα Τοξικολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85095542
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh91005229
heal.keywordURI	http://lod.nal.usda.gov/23588
heal.keywordURI	http://lod.nal.usda.gov/28292
heal.contributorName	Κουτής, Χαρίλαος	el
heal.identifier.secondary	Doi: 10.1177/0960327108102047
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας.Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Yγιεινής).	el
heal.publicationDate	2008
heal.bibliographicCitation	Tsatsakis, A. M., Tzatzarakis, M.N., Tutudaki, M., Babatsikou, F.P., Agelakis, A., et al. (2008). Assessment of levels of organochlorine pesticides and their metabolites in the hair of a Greek rural human population. "Human and Experimental Toxicology". Vol. 27(12): pp.993-940.	en
heal.abstract	We present the assessment of chronic exposure of the rural population of Helia Peloponnesus, Greece to banned organochlorine pesticides, hexachlorocyclohexane (HCH), and 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT), using hair analysis. A total of 222 head hair samples were collected and analyzed for the presence of those organochlorine pesticides and their metabolites or isomers. Gas chromatography coupled to mass spectrometry was used to measure the levels of the pollutants. The median concentrations of α-HCH, hexachlorobenzene, lindane, ortho para 1,1-dichloro-2,2-bis-(4-chlorophenyl)ethylene (opDDE), para para 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (ppDDE), ortho para 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (opDDD), para para 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (ppDDD) + ortho para 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-ethane, and para para 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-ethane were determined at 40.4, 19.7, 124.2, 6.2, 7.8, 73.1, 8.0, and 5.7 pg/mg. The median concentration of total HCHs and DDTs were 117.8 pg/mg and 9.4 pg/mg, respectively. The levels of total HCHs were much higher than the levels of DDTs in the hair samples of the studied population. This may be attributed to the presence of lindane, a pesticide officially banned in 2002. It is interesting to see that DDTs are still traced in samples despite their use being banned for more than three decades. There was no difference in the levels of the detected pesticides in hair sampled from men or women. The concentration of HCHs remains high and relatively stable across the age groups, suggesting constant exposure until very recently. The concentration of the total DDTs and the parent compound, pp-DDT presents a statistically significant decreasing trend across the age groups.	en
heal.publisher	SAGE Publications	en
heal.journalName	Human and Experimental Toxicology	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true