Abnormal P600 in heroin addicts with
prolonged abstinence elicited during a
working memory test

dc.contributor.author	Παπαγεωργίου, Χαράλαμπος	el
dc.contributor.author	Λιάππας, Ιωάννης Α.	el
dc.contributor.author	Ασβεστάς, Παντελής Α.	el
dc.contributor.author	Βάσιος, Χρήστος	el
dc.contributor.author	Ματσόπουλος, Γεώργιος Κ.	el
dc.date.accessioned	2015-01-13T13:31:11Z
dc.date.issued	2015-01-13
dc.identifier.uri	http://hdl.handle.net/11400/3930
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	Abstinence
dc.subject	Heroin abuse
dc.subject	Αποχή
dc.subject	Εξάρτηση από την ηρωίνη
dc.title	Abnormal P600 in heroin addicts with prolonged abstinence elicited during a working memory test	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Neurology
heal.classification	Ιατρική
heal.classification	Νευρολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unescothes/C02708
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Νευρολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85060445
heal.contributorName	Νικολάου, Χρυσούλα	el
heal.contributorName	Νικήτα, Κωνσταντίνα Σ.	el
heal.contributorName	Ουζούνογλου, Νικόλαος Κ.	el
heal.contributorName	Ραμπαβίλας, Ανδρέας Δ.	el
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Τ.Ε.Ι. Αθήνας. Σχολή Τεχνολογικών Εφαρμογών. Τμήμα Μηχανικών Βιοϊατρικής Τεχνολογίας Τ.Ε.	el
heal.publicationDate	2001
heal.bibliographicCitation	Papageorgiou, C., Liappas, I., Asvestas, P., Vasios, C., Matsopoulos, G., et al. (June 2001). Abnormal P600 in heroin addicts with prolonged abstinence elicited during a working memory test.Neuroreport: Cognitive Neuroscience And Neuropsychology. 12(8). pp. 1773-1778. Lippincott Williams & Wilkins.	en
heal.abstract	The P600 component of event-related potentials, believed to be generated by anterior cingulate gyrus and basal ganglia, is considered as an index of aspects of second-pass parsing processes of information processing, having much in common with working memory (WM) systems. Moreover, dysfunction of these brain structures as well as WM deficits have been implicated in the pathophysiology of opioid addicts. The present study is focused on P600 elicited during a WM test in twenty heroin addicts with prolonged abstinence compared with an equal number of healthy controls. The results showed significantly prolonged latencies at right hemisphere, specifically at Fp2 abduction. Moreover, memory performance of patients did not differ from that of normal controls. These findings may indicate that abstinent heroin addicts manifest abnormal aspects of second-pass parsing processes as are reflected by the P600 latencies, elicited during a WM test. Additionally, the P600 might serve as a valuable investigative tool for a more comprehensive understanding of the neurobiological substrate of drug abuse.	en
heal.publisher	Lippincott Williams & Wilkins	en
heal.journalName	Neuroreport: Cognitive Neuroscience And Neuropsychology	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true