Prevention of sensitization to house dust mite by allergen avoidance in school age children

dc.contributor.author	Arshad, Hassan	en
dc.contributor.author	Bojarska, Junak, A.	en
dc.contributor.author	Τσίτουρα, Στέλλα	el
dc.contributor.author	Matthew, S.	en
dc.contributor.author	Mealy, B.	en
dc.date.accessioned	2015-01-13T16:48:37Z
dc.date.available	2015-01-13T16:48:37Z
dc.date.issued	2015-01-13
dc.identifier.uri	http://hdl.handle.net/11400/3943
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	House dust mites
dc.subject	Prevention
dc.subject	Άσθμα
dc.subject	Παιδική ηλικία
dc.subject	Ακάρεα τς οικιακής σκόνης
dc.subject	Πρόληψη
dc.subject	Ευαισθητοποίηση
dc.subject	Asthma
dc.subject	Childhood
dc.subject	Sensitization
dc.title	Prevention of sensitization to house dust mite by allergen avoidance in school age children	en
heal.type	journalArticle
heal.secondaryTitle	a randomized controlled study	en
heal.generalDescription	And the Space study group	en
heal.classification	Medicine
heal.classification	Allergy
heal.classification	Ιατρική
heal.classification	Αλλεργία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85003662
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Αλλεργία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh95001141
heal.contributorName	Karmaus, Wilfried	en
heal.contributorName	Frischer, Thomas	en
heal.contributorName	Kuehr, Joachim	en
heal.contributorName	Forster, Johannes	en
heal.contributorName	Dean, Tara	en
heal.identifier.secondary	DOI: 10.1046/j.1365-2222.2002.01378.x
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας.Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Yγιεινής).	el
heal.publicationDate	2002-06
heal.bibliographicCitation	Arshad, H., Bojarka, J.A., Tsitoura, S., Matthews, S., Mealy, B., et al. (2002) Prevention of sensitization to house dust mite by allergen avoidance in school age children: a randomized controlled study. "Clinical and Experimental Allergy." 32 (6). p. 43-849.	en
heal.abstract	BACKGROUND: Sensitization to dust mites predisposes to asthma and allergic rhinitis, and prevention of this sensitization might reduce the rising prevalence of these disorders. OBJECTIVE: To test the effectiveness of dust mite avoidance measures on the development of sensitization to dust mites in children. METHODS: As part of a multicentre study (Study of Prevention of Allergy in Children of Europe), 242 children, aged 5-7 years, in three European countries (United Kingdom, Greece and Lithuania), were randomized to prophylactic group (n = 127) and control group (n = 115). At randomization these children were required to have a family history of atopy and positive skin test to an aeroallergen but not to house dust mite. Children in the prophylactic group were provided with dust mite impermeable mattress covers and advice on environmental measures to reduce exposure to dust-mite allergen. Control group children were given non-specific advice. After 12 months a standardized questionnaire was completed and skin prick tests were performed. RESULTS: Ten children in the prophylactic group and 19 in the control group were lost to follow-up. Three of 117 (2.56%) children in the prophylactic group and nine of 96 (9.38%) in the control group developed sensitization to dust mites. Logistic regression analysis confirmed an independent effect of prophylactic measures (adjusted odds ratio (OR): 0.14, 95% confidence interval (CI): 0.03-0.79, P = 0.03). Fifteen children need to be treated to prevent sensitization in one child. CONCLUSION: Dust mite sensitization can be reduced in school age children with simple mite avoidance measures.	en
heal.publisher	Blackwell Science Ltd	en
heal.journalName	Clinical and Experimental Allergy	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true
heal.conferenceName	SPACE study group