Evidence of Increased Muscle Atrophy and Impaired
Quality of Life Parameters in Patients with Uremic
Restless Legs Syndrome

dc.contributor.author	Γιαννάκη, Χριστόφορος Δ.	el
dc.contributor.author	Σακκάς, Γεώργιος Κ.	el
dc.contributor.author	Καρατζαφέρη, Χριστίνα	el
dc.contributor.author	Χατζηγεωργίου, Γεώργιος Μ.	el
dc.contributor.author	Λαβδάς, Ελευθέριος	el
dc.date.accessioned	2015-01-15T22:08:34Z
dc.date.available	2015-01-15T22:08:34Z
dc.date.issued	2015-01-16
dc.identifier.uri	http://hdl.handle.net/11400/4108
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	Body composition
dc.subject	Ποιότητα ζωής
dc.subject	Σύνθεση του σώματος
dc.subject	Σωματική απόδοση
dc.subject	Quality of life
dc.subject	Physical performance
dc.title	Evidence of Increased Muscle Atrophy and Impaired Quality of Life Parameters in Patients with Uremic Restless Legs Syndrome	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Restless legs syndrome
heal.classification	Ιατρική
heal.classification	Σύνδρομο ανήσυχων ποδιών
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh96010873
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Σύνδρομο ανήσυχων ποδιών
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85015239
heal.contributorName	Λιακόπουλος, Βασίλειος	el
heal.contributorName	Τσιάνας, Νικόλαος	el
heal.contributorName	Κουκουλής, Γεώργιος Ν.	el
heal.contributorName	Κουτεντάκης, Γιάννης	el
heal.contributorName	Στεφανίδης, Ιωάννης	el
heal.identifier.secondary	DOI:10.1371/journal.pone.0025180
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Ραδιολογίας και Ακτινολογίας.	el
heal.publicationDate	2011-10
heal.bibliographicCitation	Giannaki, C. D., Sakkas, G. K., Karatzaferi, C., Hadjigeorgiou, G. M., Lavdas, E., et al. (2011). Evidence of Increased Muscle Atrophy and Impaired Quality of Life Parameters in Patients with Uremic Restless Legs Syndrome. "Plos One" 6 (10), p.e25180.	en
heal.abstract	Background: Restless Legs Syndrome is a very common disorder in hemodialysis patients. Restless Legs Syndrome negatively affects quality of life; however it is not clear whether this is due to mental or physical parameters and whether an association exists between the syndrome and parameters affecting survival. Methodology/Principal Findings: Using the Restless Legs Syndrome criteria and the presence of Periodic Limb Movements in Sleep (PLMS/h .15), 70 clinically stable hemodialysis patients were assessed and divided into the RLS (n = 30) and non- RLS (n = 40) groups. Physical performance was evaluated by a battery of tests: body composition by dual energy X ray absorptiometry, muscle size and composition by computer tomography, while depression symptoms, perception of sleep quality and quality of life were assessed through validated questionnaires. In this cross sectional analysis, the RLS group showed evidence of thigh muscle atrophy compared to the non-RLS group. Sleep quality and depression score were found to be significantly impaired in the RLS group. The mental component of the quality of life questionnaire appeared significantly diminished in the RLS group, reducing thus the overall quality of life score. In contrast, there were no significant differences between groups in any of the physical performance tests, body and muscle composition. Conclusions: The low level of quality of life reported by the HD patients with Restless Legs Syndrome seems to be due mainly to mental health and sleep related aspects. Increased evidence of muscle atrophy is also observed in the RLS group and possibly can be attributed to the lack of restorative sleep.	en
heal.journalName	Plos One	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true