Morphological and kinetic characteristics of dynamic contrast-enhanced MRI (DCE-MRI)
correlated with histopathological factors of breast cancer

dc.contributor.author	Βάσιου, Αικατερίνη	el
dc.contributor.author	Καναβού, Θεοδώρα	el
dc.contributor.author	Βλυχού, Μαριάννα	el
dc.contributor.author	Πουλτσίδη, Αντιγόνη	el
dc.contributor.author	Ιωάννου, Μαρία	el
dc.date.accessioned	2015-01-19T09:22:44Z
dc.date.available	2015-01-19T09:22:44Z
dc.date.issued	2015-01-19
dc.identifier.uri	http://hdl.handle.net/11400/4228
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.elsevier.com/	en
dc.subject	Magnetic resonance imaging
dc.subject	Μαστός
dc.subject	Μαγνητική τομογραφία
dc.subject	Καρκίνος
dc.subject	Μορφολογικά χαρακτηριστικά
dc.subject	Κινητικά χαρακτηριστικά
dc.subject	Breast
dc.subject	Cancer
dc.subject	Morphological features
dc.subject	Kinetic characteristics
dc.title	Morphological and kinetic characteristics of dynamic contrast-enhanced MRI (DCE-MRI) correlated with histopathological factors of breast cancer	en
heal.type	journalArticle
heal.secondaryTitle	a potential prognostic role of breast MRI?	en
heal.classification	Medicine
heal.classification	Radiology, Medical
heal.classification	Ιατρική
heal.classification	Ακτινολογία, Ιατρική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85110777
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Ακτινολογία, Ιατρική
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85079741
heal.contributorName	Λαβδάς, Ελευθέριος	el
heal.contributorName	Αρβανίτης, Δημήτριος Λ.	el
heal.contributorName	Φεζουλίδης, Ιωάννης Β.	el
heal.identifier.secondary	DOI:10.1016/j.ejradi.2010.02.002
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Ραδιολογίας και Ακτινολογίας.	el
heal.publicationDate	2010-02
heal.bibliographicCitation	Vassiou, Κ., Kanavou, T., Vlychou, M., Poultsidi, A., Ioannou, M., et al. (2010). Morphological and kinetic characteristics of dynamic contrast-enhanced MRI (DCE-MRI) correlated with histopathological factors of breast cancer: a potential prognostic role of breast MRI? "Magnetic Reasonance Imaging". 1 (4), p.124-132.	en
heal.abstract	Purpose: To explore the correlation of morphological and kinetic DCE-MRI features with histopathological prognostic factors of invasive breast cancer. Material and methods: Fifty-one women with 57 cancerous lesions underwent DCE-MRI prior to surgery. DCE-MRI findings were interpreted with a multifactorial classification system that included morphological (shape, margins and pattern of enhancement) and kinetic characteristics (initial signal increase and post-initial behaviour of the time-signal intensity curve). Each morphological and kinetic parameter was scored with 0, 1 or 2 points and the total score was estimated. Finally each lesion was classified into one of the five categories that correspond to the five ACR BI-RADS categories. Statistical analysis was performed to correlate DCE-MR imaging parameters and histopathological findings using Fisher’s exact test and stepwise multiple regression analysis. Results: Increase of the signal intensity at the initial phase >100% was strongly correlated with positive lymph nodes (pZ0.008, OR 0.054). Types I and II time-signal intensity curves at the post-initial phase were associated with a fourfold increase in the likelihood of progesterone receptors positivity (pZ0.022, OR 4). Finally, high total score was positively correlated with affected lymph nodes (pZ0.033, OR 0.29).	en
heal.publisher	Elsevier Science Ltd	en
heal.journalName	European Journal of Radiography	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true