Effects of smoking on cardiovascular function

dc.contributor.author	Παπαθανασίου, Γεώργιος	el
dc.contributor.author	Μάμαλη, Αναστασία	el
dc.contributor.author	Παπαφλωράτος, Σπυρίδων	el
dc.contributor.author	Ζέρβα, Ευθυμία	el
dc.date.accessioned	2015-01-27T23:46:36Z
dc.date.available	2015-01-27T23:46:36Z
dc.date.issued	2015-01-28
dc.identifier.uri	http://hdl.handle.net/11400/4903
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject	Circulatory system
dc.subject	Καρδιοαγγειακή νόσος
dc.subject	Κυκλοφορικό σύστημα
dc.subject	Κάπνισμα
dc.subject	Καπνός
dc.subject	Cardiovascular disease
dc.subject	Smoking
dc.subject	Tobacco
dc.title	Effects of smoking on cardiovascular function	en
heal.type	journalArticle
heal.secondaryTitle	the role of nicotine and carbon monoxide	en
heal.classification	Medicine
heal.classification	Cardiology
heal.classification	Ιατρική
heal.classification	Καρδιολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85020214
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Καρδιολογία
heal.keywordURI	http://id.loc.gov/authorities/childrensSubjects/sj96005092
heal.identifier.secondary	E-ISSN:1791-809x
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Φυσικοθεραπείας	el
heal.publicationDate	2014
heal.bibliographicCitation	Papathanasiou, G., Mamali, A., Papafloratos, S. and Zerva, E. (2014) Effects of smoking on cardiovascular function: the role of nicotine and carbon monoxide. Health science journal. 8(2), pp.272-288.	en
heal.abstract	Smoking is a major risk factor for cardiovascular morbidity and mortality, and is considered to be the leading preventable cause of death in the world. Cigarette smoke contains more than 4000 chemical substances, including nicotine and carbon monoxide (CO) that can have harmful effects on cardiovascular function. These basic ingredients of tobacco smoke cause an increase in oxidative stress, endothelial damage and dysfunction, and are associated with significantly higher serum concentrations of total cholesterol and triglycerides, and lower levels of the cardioprotective high-density lipoprotein. By causing intravascular inflammation, smoking promotes the development of atherosclerosis and cardiovascular disease. The purpose of this article is to provide a brief description of the effects of smoking, and in particular the effects of nicotine and CO, on cardiovascular function. Nicotine deregulates cardiac autonomic function, boosts sympathetic activity, increases heart rate (HR) at rest, while blunting HR elevation during progressive exercise and lowering the maximum HR that can be achieved. At the same time, the smoking-generated CO binds with haemoglobin and myoglobin, reduces arterial O2 blood saturation, compromises the efficiency of respiratory enzymes, and causes dysfunction of the O2 production, transportation and delivery system, especially during exercise, substantially reducing the functional capacity and the performance of the circulatory system.	en
heal.journalName	Health science journal	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true