Active immunization in population

dc.contributor.author	Ρέγκλη, Αρετή	el
dc.contributor.author	Κωνσταντινίδης, Πολύδωρος Ι.	el
dc.contributor.author	Μαλλής, Παναγιώτης	el
dc.contributor.author	Γεροντάρα, Γεωργία	el
dc.contributor.author	Μάτσης, Κωνσταντίνος	el
dc.date.accessioned	2015-01-29T08:22:19Z
dc.date.available	2015-01-29T08:22:19Z
dc.date.issued	2015-01-29
dc.identifier.uri	http://hdl.handle.net/11400/5009
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://e-jst.teiath.gr/	en
dc.subject	DNA vaccination
dc.subject	DNA εμβολιασμός
dc.subject	Active immunization
dc.subject	Adjuvants
dc.subject	Tumor-antigen
dc.subject	Ενεργό ανοσοποιητικό
dc.subject	Πρόσθετα
dc.subject	Όγκο-αντιγόνο
dc.title	Active immunization in population	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Public health
heal.classification	Ιατρική
heal.classification	Δημόσια υγεία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://lod.nal.usda.gov/28292
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Δημόσια υγεία
heal.contributorName	Κωνσταντινίδης, Ιωάννης	el
heal.language	en
heal.access	free
heal.publicationDate	2010
heal.bibliographicCitation	Regkli, A., Konstadinedes, P.I., Mallis, P., Gerontara, G., Matsis, K., et al. (2010). Active immunization in population. "e-Journal of Science & Technology". [Online] 5(1): 15-25. Available from: http://e-jst.teiath.gr/	en
heal.abstract	The active immunization of population is a very important subset of the 21th century. The immunization is acted out with vaccines which are made of seedy bacteria or viruses, the same microorganisms which cause the variety of disorders in human organism. The immune system, after the entrance of these factors,is mobilized and produces antibodies in the same way as when a disease comes out. Antibodies destroy the seedy factors of the vaccine and the human body develops immunity. A very important factor is that the immunity is relatively permanent for a very long period, so when the individual is affected by the same factors causing the same disorder the immune system reacts more quickly for the elimination of the antigen by producing specific antibodies, and in this manner the immune system empowers and provides protection against future infections. Vaccines are also used in confrontation with various lethal diseases such as malignant tumors. In recent years, several researches have been acted out in developing new more efficient treatment options. Increased efforts have been made to apply immunomodulatory strategies in antitumor treatment. Such novel approach is the development of DNA vaccines for the destruction of malignant tumor by inducing humoral immune responces. The induction of specific immune responses directed against antigens expressed in tumor cells and displayed e.g., by MHC class I complexes can inhibit tumor growth and lead to tumor rejection. The use of different DNA delivery techniques and coadministration of adjuvants including cytokine genes may influence the pattern of specific immune responses induced. This might be the key to the future treatment of malignant tumors, increasing the life quality of patients and protecting them from relapses. Also very encouraging are the results from the clinical trials in animal models, the future studies may be focused in this way in order to render DNA vaccines safe for clinical use.	en
heal.publisher	Νερατζής, Ηλίας	el
heal.publisher	Σιανούδης, Ιωάννης	el
heal.journalName	e-Journal of Science & Technology	en
heal.journalName	e-Περιοδικό Επιστήμης & Τεχνολογίας	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	true