Psychophysiological evidence for altered information processing in delusional misidentification syndromes

dc.contributor.author	Παπαγεωργίου, Χαράλαμπος	el
dc.contributor.author	Βεντούρας, Ερρίκος Μ.	el
dc.contributor.author	Λύκουρας, Λευτέρης	el
dc.contributor.author	Ουζούνογλου, Νικόλαος Κ.	el
dc.contributor.author	Χριστοδούλου, Γεώργος Ν.	el
dc.date.accessioned	2015-02-02T10:59:49Z
dc.date.available	2015-02-02T10:59:49Z
dc.date.issued	2015-02-02
dc.identifier.uri	http://hdl.handle.net/11400/5464
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.elsevier.com	en
dc.subject	Capgras syndrome
dc.subject	Fregoli syndrome
dc.subject	Σύνδρομο Capgras
dc.subject	Σύνδρομο Fregoli
dc.title	Psychophysiological evidence for altered information processing in delusional misidentification syndromes	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Neurology
heal.classification	Ιατρική
heal.classification	Νευρολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unescothes/C02708
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Νευρολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2005005156
heal.identifier.secondary	doi:10.1016/S0278-5846(02)00353-6
heal.language	en
heal.access	campus
heal.recordProvider	Τ.Ε.Ι. Αθήνας. Σχολή Τεχνολογικών Εφαρμογών. Τμήμα Μηχανικών Βιοϊατρικής Τεχνολογίας Τ.Ε.	el
heal.publicationDate	2003
heal.bibliographicCitation	Papageorgiou, C., Ventouras, E., Lykouras, L., Uzunoglu, N. and Christodoulou, G. (2003). Psychophysiological evidence for altered information processing in delusional misidentification syndromes. Progress in Neuro-Pyschopharmacology & Biological Psychiatry. vol. 27. pp.365-372. Elsevier Science Ltd. Available from: http://www.sciencedirect.com [Accessed 24/12/2002]	en
heal.abstract	Recent research provides evidence that delusional misidentification syndromes (DMS) are associated with cognitive deficits. However, the underlying mechanisms of these deficits are not known. Since the P300 component of event-related potentials (ERPs) is related to fundamental aspects of working memory (WM), the present study is focused on P300 elicited during a WM test in DMS patients, as compared to those of healthy controls. Nine patients with DMS and 11 healthy controls, matched for age, sex and educational level were tested with a computerized version of the digit span test of the Wechsler batteries. Auditory ERPs were measured during the anticipatory period of the test. DMS patients showed significant reductions in P300 amplitude at the right frontal region compared to healthy controls. P300 latency in the central midline brain region was significantly prolonged in the DMS group. Each of these measures classified correctly 90% of the two groups. Moreover, the memory performance of the patient group was significantly lower, relatively to healthy controls. These findings provide evidence supporting the suggestion that DMS is associated with psychophysiological alterations occurring at the right frontal region, which mediates automatic processes, as well as with an irregular allocation of attentional resources, involving the interhemispheric circuitry, possibly due to gray matter degeneration. Finally, present work points to a need for further research investigating the characteristics, causes, course and treatment of severe cognitive deficits associated with DMS.	en
heal.publisher	Elsevier Science Ltd	en
heal.journalName	Progress in Neuro-Psychopharmacology and Biological Psychiatry	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true