Abstract: The Kerkini – Belles – Sidirokastro area, a border region of Northern Greece, has found its place on the map of ecotourist destinations only in the last decade. The creation and development of accommodation, alternate sport activities, the exploitation of mineral water resources (thermal springs), the creation of institutions for the protection and the enhancement of lake Kerkini, the emergence and promotion of local the products, the environmental education offered to visitors, especially younger ones, give the area the character of an “integrated” and complete agrotourism destination. The main reference points of this wider region are Lake Kerkini, an important wetland with rich bird life, protected by the Ramsar and Natura 2000 Conventions, as well as the natural thermal spas in Sidirokastro and Agistro. In the last decade there has been renewed investment activity regarding for the most part the establishment of small hotels and hostels, which in addition to hospitality are also active in the traditional food and beverage sector, the alternative sporting activities and the environmental awareness – education. All of these companies are family oriented, as proven by the commitment of time and the employment of the businesspeople themselves, as well as that of their family members. According to several surveys, one in five new small businesses close in the second year of operation, while 50% of them stops working in 5 -7 years after their establishment. In the region examined, until now, no company has discontinued its operations. In this paper we attempt to analyze the financial data of a representative sample of businesses, in order to draw conclusions about their viability. In particular, we focus our attention on sales by segment (hospitality, catering and other activities), the related costs and the operating profits. Our sample consists of twelve small and medium size enterprises, whose financial data cover the three year period 2006 - 2008. All financial data is obtained from those enterprises’ financial statements, as kept by their accountants - auditors and are submitted to the tax authorities.