Antidepressant and antibacterial activities of camellia sinensis (White Tea)

dc.contributor.author	Mohammad, Mamun Ur Rashid	en
dc.contributor.author	Mohammed, Aktar Sayeed	en
dc.contributor.author	Mohammad, Mainul Hassan	en
dc.contributor.author	Mohammed, Abdullah Jainul	en
dc.contributor.author	Shofiul, Azam	en
dc.date.accessioned	2015-02-12T00:00:58Z
dc.date.available	2015-02-12T00:00:58Z
dc.date.issued	2015-02-12
dc.identifier.uri	http://hdl.handle.net/11400/6082
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://e-jst.teiath.gr/	en
dc.subject	Camellia sinensis
dc.subject	White tea
dc.subject	Antidepressant
dc.subject	Antibacterial
dc.subject	Hole-cross
dc.subject	Open field
dc.subject	Thiopental sodium
dc.subject	Disc diffusion
dc.subject	Λευκό τσάι
dc.subject	Αντικαταθλιπτικό
dc.subject	Αντιβακτηριδιακό
dc.subject	Ανοικτό πεδίο
dc.subject	Νατριούχος θειοπεντάλη
dc.subject	Δίσκος διάχυσης
dc.title	Antidepressant and antibacterial activities of camellia sinensis (White Tea)	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Pharmacy
heal.classification	Ιατρική
heal.classification	Φαρμακευτική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85100603
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Φαρμακευτική
heal.keywordURI	http://lod.nal.usda.gov/21001
heal.contributorName	Masudur, Rahman	en
heal.language	en
heal.access	free
heal.publicationDate	2013
heal.bibliographicCitation	Mohammad, M.U.R., Mohammed, A.S., Mohammad, M.H., Mohammed, A.J. and Shofiul, A. (2013). Antidepressant and antibacterial activities of camellia sinensis (White Tea). "e-Journal of Science & Technology". [Online] 8(4): 39-46. Available from: http://e-jst.teiath.gr/	en
heal.abstract	The present study was designed to investigate the antidepressant potential of ethanolic extract of leaves and buds of Camellia sinensis (White tea) at 300 mg/kg doses in mice and antibacterial potential by disc diffusion method. Antidepressant activity of the ethanolic extract of white tea (EEWT) was assessed by using hole cross test, open field test and thiopental induced sleeping time test in swiss albino mice. The efficacy of extract (300mg/kg) was compared with standard anxiolytic drugs diazepam (1mg/kg) orally. The extract increased the locomotor activity of mice in open field and hole-cross test significantly (p<0.05). Moreover, the extract significantly (p<0.05) maximized onset of sleep and minimized the duration of sleeping time when administered with thiopental sodium. On the other hand, to determine antibacterial activities, the extract was tested against two Gram positive and five Gram negative bacteria at three concentrations (200, 300, 500μg/disc) through disc diffusion method. The antibacterial activities of ethanolic extract of leaves and buds of Camellia sinensis (white tea) were screened against various pathogenic bacteria such as Streptococcus agalactiae, Bacillus cereus, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Shigella sonnei, Shigella boydii by ‘disc diffusion method’. The zone of inhibition ranges from 6 to 11 mm and the highest zone of inhibition is 11mm which was found for Shigella sonnei at 500μg/disc. Ethanolic extract of Leaves and buds of Camellia sinensis (white tea) exhibited moderate to less activity against some organisms tested compared with the standard antibiotic “Kanamycin”. These findings demonstrate that the extract of leaves and buds of Camellia sinensis have significant antidepressant activity and moderate antibacterial activity.	en
heal.publisher	Νερατζής, Ηλίας	el
heal.publisher	Σιανούδης, Ιωάννης	el
heal.journalName	e-Journal of Science & Technology	en
heal.journalName	e-Περιοδικό Επιστήμης & Τεχνολογίας	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	true