Dual energy inverse mapping technique to estimate calcium-to-phoshorus mass ratio in bone quality assessment

dc.contributor.author	Σωτηροπούλου, Παναγιώτα Ι.	el
dc.contributor.author	Φούντος, Γεώργιος Π.	el
dc.contributor.author	Μαρτίνη, Νίκη Δ.	el
dc.contributor.author	Κούκου, Βάϊα Ν.	el
dc.contributor.author	Μιχαήλ, Χρήστος Μ.	el
dc.date.accessioned	2015-02-14T17:05:46Z
dc.date.available	2015-02-14T17:05:46Z
dc.date.issued	2015-02-14
dc.identifier.uri	http://hdl.handle.net/11400/6267
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://e-jst.teiath.gr/	en
dc.subject	Bone quality
dc.subject	Dual energy X-ray
dc.subject	X-ray simulations
dc.subject	Nonlinear functions
dc.subject	Ca/P mass ratio
dc.subject	Ποιότητα οστών
dc.subject	Ακτίνες Χ διπλής ενέργειας
dc.subject	Προσομοιώσεις ακτίνων Χ
dc.subject	Μη γραμμικές λειτουργίες
dc.subject	Αναλογία μάζας Ca/P
dc.title	Dual energy inverse mapping technique to estimate calcium-to-phoshorus mass ratio in bone quality assessment	en
heal.type	journalArticle
heal.generalDescription	Special issue: 2nd Conference on Bio-Medical Instrumentation and related Engineering And Physical Sciences, Technological Educational Institute of Athens, Athens, 21 & 22 June 2013.	en
heal.classification	Science
heal.classification	Physics
heal.classification	Επιστήμες
heal.classification	Φυσική
heal.classificationURI	http://zbw.eu/stw/descriptor/15685-2
heal.classificationURI	http://zbw.eu/stw/descriptor/15669-0
heal.classificationURI	N/A-Επιστήμες
heal.classificationURI	N/A-Φυσική
heal.contributorName	Βαλαής, Ιωάννης Γ.	el
heal.contributorName	Κανδαράκης, Ιωάννης Σ.	el
heal.contributorName	Νικηφορίδης, Γεώργιος Χ.	el
heal.language	en
heal.access	free
heal.publicationDate	2014
heal.bibliographicCitation	Sotiropoulou, P.I., Fountos, G.P., Martini, N.D., Koukou, V.N., Michail, C.M., et al. (2014). Dual energy inverse mapping technique to estimate calcium-to-phoshorus mass ratio in bone quality assessment. "e-Journal of Science & Technology". [Online] 9(4): 15-24. Available from: http://e-jst.teiath.gr/	en
heal.abstract	Bone quality is a broad term encompassing factors affecting the structural and material properties of bone. X-ray dual-energy method (XDEM) provides one way to explore bone quality in terms of bone tissue material properties. In this study a XDEM is presented for the determination of Ca/P mass ratio, parameter which appears to play an important role in bone health. The low- and high-energy intensity measurements were combined, using a nonlinear mapping function, to cancel out the soft tissue structures and generate the dual energy (DE) Ca/P mass ratio value. The total entrance-skin exposure from low- and high-energy measurements was constrained so that it is similar to diagnostic-examination levels. The DE simulated data were exported using variable Ca and PO4 thicknesses, while the tissue thickness was kept constant. The thickness of each material was fitted separately using a nonlinear least squares minimization algorithm. The functional forms of inverse functions that have been investigated are the linear, quadratic, cubic, and conic functions. The inversemapping functions were found to vary as analytic functions of second (conic) and third (conic) order. A nonlinear eight term rational function was selected for dual energy calibration which appeared to be capable of high fitting accuracy while requiring relative few terms.	en
heal.publisher	Νερατζής, Ηλίας	el
heal.publisher	Σιανούδης, Ιωάννης	el
heal.publisher	Βαλαής, Ιωάννης Γ.	el
heal.publisher	Φούντος, Γεώργιος Π.	el
heal.journalName	e-Journal of Science & Technology	en
heal.journalName	e-Περιοδικό Επιστήμης & Τεχνολογίας	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	true