Application of high performance liquid chromatography to the analysis of cilazapril in bulk and pharmaceutical formations

dc.contributor.author	Lavudu, Petikam	en
dc.contributor.author	Rani, Avula Prameela	en
dc.contributor.author	Sekaran, Chandra Bala	en
dc.date.accessioned	2015-02-17T07:22:10Z
dc.date.available	2015-02-17T07:22:10Z
dc.date.issued	2015-02-17
dc.identifier.uri	http://hdl.handle.net/11400/6399
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://e-jst.teiath.gr/	en
dc.subject	Cilazapril
dc.subject	Cyano column
dc.subject	HPLC analysis
dc.subject	Pharmaceutical formulations
dc.subject	Σιλαζαπρίλη
dc.subject	Φαρμακευτικές συνθέσεις
dc.title	Application of high performance liquid chromatography to the analysis of cilazapril in bulk and pharmaceutical formations	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Pharmacy
heal.classification	Ιατρική
heal.classification	Φαρμακευτική
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85100603
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Φαρμακευτική
heal.language	en
heal.access	free
heal.publicationDate	2014
heal.bibliographicCitation	Lavudu, P., Rani, A.P. and Sekaran, C.B. (2014). Application of high performance liquid chromatography to the analysis of cilazapril in bulk and pharmaceutical formations. "e-Journal of Science & Technology". [Online] 9(5): 137-146. Available from: http://e-jst.teiath.gr/	en
heal.abstract	A rapid, selective, precise and accurate high-performance liquid chromatography method for the estimation of cilazapril (CZP) in bulk and pharmaceutical formulations has been developed and validated. The assay of the cilazapril was performed on a Cyano Column (150 mm x 4.6 mm, 5 μm particle size) with UV detection at 212 nm. The mobile phase consists of a formate buffer (pH 3.75)-acetonitrile (60:40 v/v) and a flow rate of 1 ml/min was maintained. The calibration curve was linear over the range of 2–200 μg/ml (r 2 = 0.9990). The proposed method was validated as per International Conference on Harmonization guidelines. The proposed method was successfully applied to the quantification of (CZP) in pharmaceutical formulations. The proposed method will be useful for routine quality control analysis of (CZP).	en
heal.publisher	Νερατζής, Ηλίας	el
heal.publisher	Σιανούδης, Ιωάννης	el
heal.journalName	e-Journal of Science & Technology	en
heal.journalName	e-Περιοδικό Επιστήμης & Τεχνολογίας	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	true