Intraoperative radiotherapy as accelerated partial breast irradiation for early breast cancer

dc.contributor.author	Sautter-Bihl, Marie-Luise	en
dc.contributor.author	Sedlmayer, Felix	en
dc.contributor.author	Budach, Wilfried	en
dc.contributor.author	Dunst, Jürgen	en
dc.contributor.author	Engenhart-Cabillic, Rita	en
dc.date.accessioned	2015-02-23T23:26:33Z
dc.date.available	2015-02-23T23:26:33Z
dc.date.issued	2015-02-24
dc.identifier.uri	http://hdl.handle.net/11400/6820
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://link.springer.com/	en
dc.subject	Breast cancer
dc.subject	Accelerated partial breast irradiation
dc.subject	Καρκίνος μαστού
dc.subject	Ταχεία μερική ακτινοβόληση του μαστού
dc.title	Intraoperative radiotherapy as accelerated partial breast irradiation for early breast cancer	en
heal.type	journalArticle
heal.classification	Pharmacology
heal.classification	Radiology, Medical
heal.classification	Φαρμακολογία
heal.classification	Ακτινολογία, Ιατρική
heal.classificationURI	http://skos.um.es/unescothes/C02967
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85110777
heal.classificationURI	N/A-Φαρμακολογία
heal.classificationURI	N/A-Ακτινολογία, Ιατρική
heal.contributorName	Fietkau, Rainer	en
heal.contributorName	Feyer, Petra	en
heal.contributorName	Haase, Wulf	en
heal.contributorName	Harms, Wolfgang	en
heal.contributorName	Rödel, Claus	en
heal.contributorName	Souchon, Rainer	en
heal.contributorName	Wenz, Frederik	en
heal.contributorName	Sauer, Rolf	en
heal.identifier.secondary	DOI 10.1007/s00066-010-8001-2
heal.language	en
heal.access	campus
heal.recordProvider	Τ.Ε.Ι. Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ραδιολογίας και Ακτινολογίας.	el
heal.publicationDate	2010
heal.bibliographicCitation	Sautter-Bihl, M., Sedlmayer, F., Budach, W., Dunst, J., Engenhart-Cabillic, R., et al. (December 2010). Intraoperative radiotherapy as accelerated partial breast irradiation for early breast cancer. Strahlentherapie und Onkologie. 186(12). pp. 651-657. Springer-Verlag:2010. Available from: http://link.springer.com/ [Accessed 29/11/2010]	en
heal.abstract	Intraoperative radiotherapy (IORT) was originally introduced in breast cancer treatment as an “anticipated boost” during the procedure of breast conserving surgery (BCS). In addition to whole breast irradiation (WBI), it has yielded excellent long-term results [31, 38]. Under the assumption that the majority of in-breast tumor recurrences (IBTR) occur in the originally affected site, accelerated partial breast irradiation (APBI) as the sole treatment modality was initiated in several studies and with different techniques, one of which was IORT first with electrons, later also with conventional x-rays [29]. The question whether and for whom the gold standard of WBI may be replaced by APBI – especially IORT – alone has recently been one of the most controversial issues of adjuvant therapy for breast cancer. Two recently published studies by Veronesi et al. [36] and Vaidya et al. [35] presenting shortterm results of single shot IORT with electrons (ELIOT) and with an orthovoltage system (TARGIT), respectively, have further invigorated this discussion as illustrated by several letters to the editor commenting on the TARGIT study. While Vaidya et al. [35] indicate their results of IORT alone as “an alternative to WBI for selected patients” and one editorial even proclaims it as standard [6], all the authors of the respective letters [10, 16, 27, 33] strongly disagree with this conclusion. The present editorial comments on the two publications and, furthermore, provides respective statements of the breast cancer expert panel of the German Society of Radiation Oncology (DEGRO).	en
heal.publisher	Springer-Verlag	en
heal.journalName	Strahlentherapie und Onkologie	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true