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dc.contributor.author Μπασταρδής-Ζάκας, Κ. el
dc.contributor.author Ιατράκης, Γεώργιος Μ. el
dc.contributor.author Ναυρόζογλου, Ιορδάνης el
dc.contributor.author Πεϊτσίδης, Παναγιώτης el
dc.contributor.author Σαλάκος, Νικόλαος el
dc.date.accessioned 2015-02-26T09:17:56Z
dc.date.issued 2015-02-26
dc.identifier.uri http://hdl.handle.net/11400/6943
dc.rights Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.source http://www.ncbi.nlm.nih.gov/pubmed/21355457 el
dc.subject Mammography before 50 years old
dc.subject Screening mammography
dc.subject Mammography in young women
dc.subject Μαστογραφία πριν τα 50 έτη
dc.subject Μαστογραφία προσυμπτωματικού ελέγχου
dc.subject Μαστογραφία σε νεαρές γυναίκες
dc.title Maximizing the benefits of screening mammography for women 40-49 years old en
heal.type journalArticle
heal.classification Medicine
heal.classification Midwifery
heal.classification Ιατρική
heal.classification Μαιευτική
heal.classificationURI http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI http://id.loc.gov/authorities/subjects/sh96006072
heal.classificationURI **N/A**-Ιατρική
heal.classificationURI **N/A**-Μαιευτική
heal.contributorName Μαλακάσσης, Πέτρος el
heal.contributorName Ζερβούδης, Στέφανος el
heal.identifier.secondary ISSN:0390-6663
heal.dateAvailable 10000-01-01
heal.language en
heal.access forever
heal.recordProvider Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας.Σχολή Επαγγελμάτων Υγείας και Πρόνοιας.Τμήμα Μαιευτικής el
heal.publicationDate 2010
heal.bibliographicCitation Bastardis-Zakas, K., Iatrakis, G., Navrozoglou, I., Peitsidis, P., Salakos, N., et.al.(2010).Maximizing the benefits of screening mammography for women 40-49 years old.Clinical and Experimental Obstetrics Gynecology 37(4).pp 278-282.Canada: I.R.O.G. el
heal.abstract BACKGROUND: While women aged 50 and older are broadly considered to benefit from screening mammograms, the evidence of any similar advantages for younger women are still considered insufficient to form any substantial conclusions on the matter. The primary goal of this study was to examine whether or not the mortality rate of younger women is benefited by mammography, and if so, how can this beneficial effect be maximized. METHODS: The authors have taken into account all available randomized control trials (RCTs) and have conducted a meta-analysis based on those RCTs to study the effect of mammography on the mortality rate of women younger than age 50. Further interpretation on various aspects of the results has also led to separate meta-analyses, with the RCTs included grouped in accordance to the mean time interval between screening mammograms employed by each study. The findings and conclusions of the comparison were used to calculate the number of mammograms necessary to reduce the absolute death risk, depending on the time interval between screening mammograms. RESULTS: The meta-analysis indicated a reduction in breast-cancer mortality in the intervention group, which reached statistical significance (relative risk (RR) 0.81 [95% CI 0.71-0.93] p < 0.01). Furthermore, when the RCTs included were grouped according to their mean time interval between mammograms, there was a definite increase of statistical significance in favor of those RCTs with shorter interval times (RR 0.76 [95% CI 0.64-0.89] p < 0.01). CONCLUSIONS: The significant mortality rate reduction demonstrated by the meta-analytical results is a key indicator of the beneficial effect of mammography on the age group of women younger than 50. Additionally, the increase in the aforesaid significance when combining RCTs with short time intervals between mammograms, as opposed to those RCTs with longer intervals, suggests that the optimal use of mammographic screening lies with the former. This is better demonstrated when taking in account our approach to answering the practical question of "how many screening mammograms will take to save one life?" in correlation with the mean time interval involved. en
heal.publisher I.R.O.G. en
heal.journalName Clinical and Experimental Obstetrics Gynecology en
heal.journalType peer-reviewed
heal.fullTextAvailability true


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Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες Except where otherwise noted, this item's license is described as Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες