Risk of upper aerodigestive tract cancer and type of alcoholic beverage

dc.contributor.author	Marron, Manuela	en
dc.contributor.author	Boffetta, Paolo	en
dc.contributor.author	Møller, Henrik	en
dc.contributor.author	Ahrens, Wolfgang	en
dc.contributor.author	Pohlabeln, Hermann	en
dc.date.accessioned	2015-04-19T09:15:45Z
dc.date.issued	2015-04-19
dc.identifier.uri	http://hdl.handle.net/11400/8538
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.springer.com/gp/	en
dc.subject	Αλκοόλ
dc.subject	Alcohol
dc.title	Risk of upper aerodigestive tract cancer and type of alcoholic beverage	en
heal.type	journalArticle
heal.secondaryTitle	a European multicenter case-control study	en
heal.classification	Medicine
heal.classification	Oncology
heal.classification	Ιατρική
heal.classification	Ογκολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85094724
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Ογκολογία
heal.contributorName	Benhamou, Simone	en
heal.contributorName	Bouchardy, Christine	en
heal.contributorName	Λάγιου, Παγώνα, Δ. (1967-)	el
heal.contributorName	Λάγιου, Αρετή	el
heal.contributorName	Slámová, Alena	en
heal.contributorName	Schejbalová, Miriam	en
heal.contributorName	Merletti, Franco	en
heal.contributorName	Richiardi, Lorenzo	en
heal.contributorName	Kjaerheim, Kristina	en
heal.contributorName	Agudo, Antonio	en
heal.contributorName	Castellsague, Xavier	en
heal.contributorName	Victorovna - Macfarlane, Tatiana	en
heal.contributorName	Macfarlane, Gary John	en
heal.contributorName	Talamini, Renato	en
heal.contributorName	Barzan, Luigi	en
heal.contributorName	Canova, Cristina	en
heal.contributorName	Simonato, Lorenzo	en
heal.contributorName	Biggs, Anne Marie	en
heal.contributorName	Thomson, Peter	en
heal.contributorName	Conway, David Ian	en
heal.contributorName	McKinney, Patricia Ann	en
heal.contributorName	Znaor, Ariana	en
heal.contributorName	Healy, Claire Marie	en
heal.contributorName	McCartan, Bernard Eugene	en
heal.contributorName	Brennan, Paul	en
heal.contributorName	Hashibe, Mia	en
heal.identifier.secondary	DOI: 10.1007/s10654-012-9699-1
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής)	el
heal.publicationDate	2012-07
heal.bibliographicCitation	Marron, M., Boffetta, P., Møller, H., Ahrens, W., Pohlabeln, H., et al. (2012) Risk of upper aerodigestive tract cancer and type of alcoholic beverage: a European multicenter case-control study. "European Journal of Epidemiology", 27 (7), p. 499-517. Available from: http://link.springer.com/article/10.1007%2Fs10654-012-9699-1 [Accessed: 19/04/2015]	en
heal.abstract	The general relationship between cancers of the upper aerodigestive tract (UADT) and alcohol drinking is established. Nevertheless, it is uncertain whether different types of alcoholic beverages (wine, beer and liquor) carry different UADT cancer risks. Our study included 2,001 UADT cancer cases and 2,125 controls from 14 centres in 10 European countries. All cases were histologically or cytologically confirmed squamous cell carcinomas. Controls were frequency matched by sex, age and centre. Logistic regression models were used to estimate odds ratios (OR) and 95 % confidence intervals (95 %CI) adjusted for age, sex, centre, education level, vegetable and fruit intake, tobacco smoking and alcohol drinking, where appropriate. Risk of beverage-specific alcohol consumption were calculated among ‘pure drinker’ who consumed one beverage type exclusively, among ‘predominant drinkers’ who consumed one beverage type to more than 66 % and among ‘mixed drinkers’ who consumed more than one beverage type to similar proportions. Compared to never drinkers and adjusted for cumulative alcohol consumption, the OR and 95 %CI for wine, beer and liquor drinking, respectively, were 1.24 (0.86, 1.78), 1.54 (1.05, 2.27) and 0.94 (0.53, 1.64) among ‘pure drinkers’ (p value for heterogeneity across beverage types = 0.306), 1.05 (0.76,1.47), 1.25 (0.87,1.79) and 1.43 (0.95, 2.16) among ‘predominant drinkers’ (p value = 0.456), and 1.09 (0.79, 1.50), 1.20 (0.88, 1.63) and 1.12 (0.82, 1.53) among ‘mixed drinkers’ (p value = 0.889). Risk of UADT cancer increased with increasing consumption of all three alcohol beverage types. Our findings underscore the strong and comparable carcinogenic effect of ethanol in wine, beer and liquor on organs of the UADT.	en
heal.journalName	European Journal of Epidemiology	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false