The aetiology of upper aerodigestive tract cancers among young adults in Europe

dc.contributor.author	Victorovna Macfarlane, Tatiana	en
dc.contributor.author	Macfarlane, Gary John	en
dc.contributor.author	Oliver, Richard, J.	en
dc.contributor.author	Benhamou, Simone	en
dc.contributor.author	Bouchardy, Christine	en
dc.date.accessioned	2015-04-19T15:48:23Z
dc.date.issued	2015-04-19
dc.identifier.uri	http://hdl.handle.net/11400/8567
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.springer.com/gp/	en
dc.subject	Cancer
dc.subject	Καρκίνος
dc.title	The aetiology of upper aerodigestive tract cancers among young adults in Europe	en
heal.type	journalArticle
heal.secondaryTitle	the ARCAGE study	en
heal.classification	Medicine
heal.classification	Oncology
heal.classification	Ιατρική
heal.classification	Ογκολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unesco6/320713
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Ογκολογία
heal.contributorName	Ahrens, Wolfgang	en
heal.contributorName	Pohlabeln, Hermann	en
heal.contributorName	Λάγιου, Παγώνα, Δ. (1967-)	el
heal.contributorName	Λάγιου, Αρετή	el
heal.contributorName	Castellsague, Xavier	en
heal.contributorName	Agudo, Antonio	en
heal.contributorName	Merletti, Franco	en
heal.contributorName	Richiardi, Lorenzo	en
heal.contributorName	Kjaerheim, Kristina	en
heal.contributorName	Slamova, Alena	en
heal.contributorName	Schejbalova, Miriam	en
heal.contributorName	Canova, Cristina	en
heal.contributorName	Simonato, Lorenzo	en
heal.contributorName	Talamini, Renato	en
heal.contributorName	Barzan, Luigi	en
heal.contributorName	Conway, David Ian	en
heal.contributorName	McKinney, Patricia Ann	en
heal.contributorName	Znaor, Ariana	en
heal.contributorName	Lowry, Raymond James	en
heal.contributorName	Thomson, Peter	en
heal.contributorName	Healy, Claire Marie	en
heal.contributorName	McCartan, Bernard Eugene	en
heal.contributorName	Marron, Manuela	el
heal.contributorName	Hashibe, Mia	en
heal.contributorName	Brennan, Paul	en
heal.identifier.secondary	DOI: 10.1007/s10552-010-9641-3
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής)	el
heal.publicationDate	2010-12
heal.bibliographicCitation	Victorovna Macfarlane, T., Macfarlane, G., Oliver, R., Benhamou, S., Bouchardy, C., et al. (2010) The aetiology of upper aerodigestive tract cancers among young adults in Europe: the ARCAGE study. "Cancer Causes and Control", 21 (12), p. 2213-2221. Available from: http://link.springer.com/article/10.1007%2Fs10552-010-9641-3 [Accessed: 19/05/2015]	en
heal.abstract	Background The incidence of cancers of the upper aerodigestive tract (UADT) is increasing throughout the world. To date the increases have been proportionally greatest among young people. Several reports have suggested that they often do not have a history of tobacco smoking or heavy alcohol consumption. Objective To determine the contribution of lifestyle factors to the etiology of UADT cancers occurring in those aged less than 50 years. Methods A case–control study was conducted in 10 European countries. Cases were cancers of the oral cavity and pharynx, larynx and esophagus, and hospital or population controls were age and sex matched. Results There were 356 cases younger than 50 years and 419 controls. Risk was strongly related to current smoking [odds ratio (OR) 5.5 95%; confidence interval (CI) (3.3, 9.2)], and risk increased with number of pack-years smoked. Risk was also related to alcohol consumption for both current (OR 1.8; 0.97, 3.3) and past (OR 3.4; 1.6, 7.4) drinkers, and risk increased with number of drink-years. Persons frequently consuming fruits and vegetables were at significantly reduced risk. Conclusions Risk factors already identified as being important for UADT cancers in adults are also important influences on risk in younger adults. The implication of these results is that the public health message in preventing UADT cancers remains the same to young and old alike.	en
heal.journalName	Cancer Causes and Control	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false