Diet and expression of estrogen alpha and progesterone receptors in the normal mammary gland

dc.contributor.author	Λάγιου, Παγώνα, Δ. (1967-)	el
dc.contributor.author	Σαμόλη, Ευαγγελία	el
dc.contributor.author	Γεωργίλα, Χριστίνα	el
dc.contributor.author	Ζουρνά, Παντελίνα	el
dc.contributor.author	Μπαρμπούνη, Αναστασία, Κ.	el
dc.date.accessioned	2015-04-19T16:41:50Z
dc.date.issued	2015-04-19
dc.identifier.uri	http://hdl.handle.net/11400/8571
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.springer.com/gp/	en
dc.subject	Oncology
dc.subject	Cancer
dc.subject	Ογκολογία
dc.subject	Καρκίνος
dc.title	Diet and expression of estrogen alpha and progesterone receptors in the normal mammary gland	en
heal.type	journalArticle
heal.classification	Biology
heal.classification	Nutrition
heal.classification	Βιολογία
heal.classification	Διατροφή
heal.classificationURI	http://zbw.eu/stw/descriptor/15633-0
heal.classificationURI	http://skos.um.es/unescothes/C02780
heal.classificationURI	N/A-Βιολογία
heal.classificationURI	N/A-Διατροφή
heal.keywordURI	http://skos.um.es/unesco6/320713
heal.contributorName	Γκιόκας, Γεώργιος	el
heal.contributorName	Βασιλάρου, Ντόροθυ Σταματία	el
heal.contributorName	Τσικκίνης, Αννίβας, Χ.	el
heal.contributorName	Σφήκας, Κωνσταντίνος	el
heal.contributorName	Σέκερης, Κωνσταντίνος, Ε. (1933-2009)	el
heal.contributorName	Hsieh, Chung Cheng	el
heal.contributorName	Adami, Hans Olov	en
heal.contributorName	Τριχόπουλος, Δημήτρης, Β. (1938-2014)	el
heal.identifier.secondary	DOI: 10.1007/s10552-008-9269-8
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής)	el
heal.publicationDate	2009-07
heal.bibliographicCitation	Lagiou, P., Samoli, E., Lagiou, A., Georgila, C., Zourna, P., et al (2009) Diet and expression of estrogen alpha and progesterone receptors in the normal mammary gland. "Cancer Causes and Control", 20 (5), p. 601-607. Available from: http://link.springer.com/article/10.1007%2Fs10552-008-9269-8 [Accessed: 19/04/2015]	en
heal.abstract	Objective It has been recently reported that expression of estrogen alpha (ER-α) and progesterone (PR) receptors in the normal mammary gland is inversely associated with breast cancer risk among postmenopausal women. We investigated whether dietary intakes are associated with the expression of ER-α and PR receptors in the apparently normal, as opposed to pathological, mammary tissue. Methods In a study in Greece, we examined associations of dietary intakes with ER-α and PR expression in the adjacent-to-pathological apparently normal mammary tissue of 562 women with either breast cancer (267 women) or BBD (299 women). Diet was assessed through an extensive food frequency questionnaire and results were analyzed using multiple logistic regression. Results Monounsaturated (p = 0.03) and, to a lesser extent, polyunsaturated lipids (p = 0.08) were positively associated with ER-α expression. Cereals and starchy roots were inversely associated with ER-α (p = 0.01), whereas milk and dairy products were inversely associated with PR expression (p = 0.02). Ethanol intake was non-significantly inversely associated with ER-α expression (p = 0.07). Conclusions Our findings suggest that the weak associations of diet with breast cancer risk could be explained, to some extent, by effects of diet on receptor expression in the normal mammary gland.	en
heal.journalName	Cancer Causes and Control	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false