Flavonoid intake and liver cancer

dc.contributor.author	Λάγιου, Παγώνα, Δ. (1967-)	el
dc.contributor.author	Rossi, Marta	en
dc.contributor.author	Λάγιου, Αρετή	el
dc.contributor.author	Τζώνου, Αναστασία	el
dc.contributor.author	La Vecchia, Carlo	en
dc.date.accessioned	2015-04-19T18:06:24Z
dc.date.issued	2015-04-19
dc.identifier.uri	http://hdl.handle.net/11400/8576
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.springer.com/gp/	en
dc.subject	Epidemics
dc.subject	Επιδημιολογία
dc.title	Flavonoid intake and liver cancer	en
heal.type	journalArticle
heal.secondaryTitle	a case–control study in Greece	en
heal.classification	Medicine
heal.classification	Nutrition
heal.classification	Ιατρική
heal.classification	Διατροφή
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unescothes/C02780
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Διατροφή
heal.keywordURI	http://skos.um.es/unescothes/C01402
heal.contributorName	Τριχόπουλος, Δημήτρης, Β. (1938-2014)	el
heal.identifier.secondary	DOI: 10.1007/s10552-008-9144-7
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής)	el
heal.publicationDate	2008-10
heal.bibliographicCitation	Lagiou, P., Rossi, M., Lagiou, A., Tzonou, A., La Vecchia, C., et al (2008) Flavonoid intake and liver cancer: a case–control study in Greece. "Cancer Causes & Control", 19 (8), p. 813-818. Available from: http://link.springer.com/article/10.1007%2Fs10552-008-9144-7 [Accessed: 19/04/2015]	en
heal.abstract	In the context of a case–control study undertaken in Greece, we examined the role of six flavonoid classes in the etiology of hepatocellular carcinoma (HCC), by viral status, and of cholangiocarcinoma (CAC). Data and blood samples were collected between 1995 and 1998. Information about dietary intakes and covariates, including chronic infection with hepatitis B (HBV) and C (HCV) virus, were available for 250 HBV and/or HCV positive HCC cases, 83 HBV and HCV negative HCC cases, six CAC cases, and 360 hospital controls. In logistic regression models including gender, age, education, tobacco smoking, and total energy intake, there were no distinct patterns with respect to either HCC virus positive and HCC virus negative in relation to total flavonoids or any class of flavonoids, with the exception of flavones. Flavone intake, mostly derived from spinach and peppers, was inversely associated with both virus positive (P-trend, 0.049) and virus negative (P-trend, 0.084) HCC. There was also a suggestion of an inverse association of CAC with flavan-3-ols, anthocyanidins, and total flavonoids which, however, has to be taken with due caution on account of the small number of cases of this rare tumor. We conclude that flavones may be inversely associated with HCC risk, irrespective of its dominant etiology (viral or non viral).	en
heal.journalName	Cancer Causes & Control	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false