Randomized trial to prevent sensitization to mite allergens in toddlers and preschoolers by allergen reduction and education

dc.contributor.author	Τσίτουρα, Στέλλα	el
dc.contributor.author	Νεστορίδου, Αικατερίνη	el
dc.contributor.author	Μπότης, Παναγιώτης	el
dc.contributor.author	Karmaus, Wilfried	en
dc.contributor.author	Boteza, Calin	en
dc.date.accessioned	2015-04-23T16:53:50Z
dc.date.available	2015-04-23T16:53:50Z
dc.date.issued	2015-04-23
dc.identifier.uri	http://hdl.handle.net/11400/8775
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://archpedi.jamanetwork.com	en
dc.subject	Toddlers--Care
dc.subject	Education
dc.subject	ευαισθητοποίηση
dc.subject	δοκιμή
dc.subject	αλλεργιογόνο ακάρεων
dc.subject	μικρά παιδιά
dc.subject	επιμόρφωση
dc.subject	sensitization
dc.subject	trial
dc.subject	mite allergen
dc.title	Randomized trial to prevent sensitization to mite allergens in toddlers and preschoolers by allergen reduction and education	en
heal.type	journalArticle
heal.secondaryTitle	one-year results	el
heal.classification	Ιατρική
heal.classification	Εσωτερική παθολογία
heal.classification	Medicine
heal.classification	Internal medicine
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Εσωτερική παθολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85067347
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh2010116589
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85040989
heal.contributorName	Bojarskas, Jurgis	en
heal.contributorName	Arshad, Hassan	en
heal.contributorName	Kuehr, Joachim	en
heal.contributorName	Forster, Johannes	en
heal.identifier.secondary	DOI:10.1001/archpedi.156.10.1021.
heal.language	en
heal.access	free
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής)	el
heal.publicationDate	2002-10
heal.bibliographicCitation	Tsitoura, S., Nestoridou, K., Botis, P., Karmaus, W., Botezan, C.,et al. (2002). Randomized trial to prevent sensitization to mite allergens in toddlers and preschoolers by allergen reduction and education: one-year results. "Archives of Pediatrics and Adolescent Medicine" 156(10): 1021-1027	en
heal.abstract	Objective To evaluate the effectiveness of prevention measures against dust mite sensitization. Design European (England, Germany, Greece, Lithuania) multicenter prospective single-blind randomized control trial with a follow-up of 12 months. Participants Toddlers and preschoolers, with at least 1 parent with atopic symptoms and sensitization, who initially were not sensitized to mite allergens. Interventions A combination of education and a simple preventive measure (mattress encasement) to reduce mite allergen exposure. Setting Community-based study. Main Outcome Measures Sensitization to mite allergens (skin-prick test or specific immunoglobulin E). Results Of 636 children (mean age, 3.1 years) included in the study, 566 (89%) participated in the first-year follow-up. The incidence of sensitization to mite allergens was 10 (3%) of 330 in the intervention vs 20 (6.5%) of 306 in the control arm, including loss of follow-up (intention-to-treat principle). Allergic symptoms were more common in sensitized than in nonsensitized children and so was the prevalence of physician-diagnosed asthma, eczema, and food allergy. Conclusions This simple, harmless, and inexpensive measure can be used in toddlers and preschoolers of parents with atopic disorders to reduce sensitization to mite allergens. With regard to clinical manifestations of atopy, follow-up studies are needed to determine the effectiveness of the intervention.	en
heal.journalName	Archives of Pediatrics and Adolescent Medicine	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false