The influence of magnesium ascorbyl phosphate on moisturization of stratum corneum

dc.contributor.author	Βαρβαρέσου, Αθανασία	el
dc.contributor.author	Τσιριβάς, Ευθύμιος	el
dc.contributor.author	Τσαουλά, Ελεάνα	el
dc.contributor.author	Πρωτόπαπα, Ευαγγελία Ε.	el
dc.date.accessioned	2015-04-29T14:51:11Z
dc.date.issued	2015-04-29
dc.identifier.uri	http://hdl.handle.net/11400/9260
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	www.scopus.com	en
dc.subject	Καλλυντικά
dc.subject	Δερματικές αντιδράσεις
dc.subject	Ενυδάτωση
dc.subject	Skin reactions
dc.title	The influence of magnesium ascorbyl phosphate on moisturization of stratum corneum	en
heal.type	journalArticle
heal.classification	Aesthetics
heal.classification	Cosmetics
heal.classification	Αισθητική
heal.classification	Κοσμητολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85001441
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85033139
heal.classificationURI	N/A-Αισθητική
heal.classificationURI	N/A-Κοσμητολογία
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.publicationDate	2005-11-05
heal.bibliographicCitation	Varvaresou, A., Tsirivas, E., Tsaoula, E. and Protopapa, E. (2005) The influence of magnesium ascorbyl phosphate on moisturization of stratum corneum. "Review of Clinical Pharmacology and Pharmacokinetics", International Edition, 19 (3), p.139-142	en
heal.abstract	The antioxidant activity of L-ascorbic acid is well established. Topical application of vitamin C has been shown to provide photoprotection, to decrease radiation damage and to prevent UV immunosuppression. L-ascorbic acid was found to stimulate collagen synthesis in monolayer fibroblast cultures and to enhance the hydration of the stratum corneum, as well. The magnesium salt of ascorbyl-2-phosphate (MAP) is a stable derivative of ascorbic acid, which was found to be equivalent to ascorbic acid in stimulating collagen synthesis in monolayer fibroblast cultures. Furthermore, the epidermal transportation and conversion of MAP to L-ascorbic acid has been proved in humans, as well. Although several studies strongly support the idea that ascorbic acid enhances the hydration of stratum corneum, the hydrating properties of MAP have not been examined yet. In this study, tests were carried out in a half face, double blind manner consisting of 28 days usage (twice daily applications). According to our findings the presence of MAP compared to placebo, caused low improvement in the hydration of the skin or the concentration of moisturizing raw materials in the placebo masked its moisturizing property.	en
heal.publisher	Pharmakon Press	en
heal.journalName	Review of Clinical Pharmacology and Pharmacokinetics	el
heal.journalType	peer-reviewed
heal.fullTextAvailability	false