Synthesis and antimicrobial evaluation of indole containing derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and their open-chain counterparts

dc.contributor.author	Τσοτίνης, Ανδρέας	el
dc.contributor.author	Βαρβαρέσου, Αθανασία	el
dc.contributor.author	Καλογεροπούλου, Θεοδώρα	el
dc.contributor.author	Σιάτρα - Παπασταϊκούδη, Θεοδώρα	el
dc.contributor.author	Τιλιγαδά, Αικατερίνη	el
dc.date.accessioned	2015-04-30T13:12:16Z
dc.date.issued	2015-04-30
dc.identifier.uri	http://hdl.handle.net/11400/9320
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	https://www.thieme-connect.com	en
dc.subject	Καλλυντικά
dc.subject	Αντιμικροβιακή προστασία
dc.subject	Χημικά παρασκευάσματα
dc.subject	Cosmetics
dc.subject	Antimicrobial protection
dc.subject	Chemical preparations
dc.title	Synthesis and antimicrobial evaluation of indole containing derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and their open-chain counterparts	en
heal.type	journalArticle
heal.classification	Aesthetics
heal.classification	Chemistry
heal.classification	Αισθητική
heal.classification	Χημεία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85001441
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85022986
heal.classificationURI	N/A-Αισθητική
heal.classificationURI	N/A-Χημεία
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.publicationDate	1997-03
heal.bibliographicCitation	Tsotinis, A., Varvaresou, A., Calogeropoulou, T., Siatra-Papastaikoudi, T. and Tiligada, A. (1997) Synthesis and antimicrobial evaluation of indole containing derivatives of 1,3,4-thiadiazole, 1,2,4-triazole and their open-chain counterparts. "Arzneimittel-Forschung/Drug Research" 47 (3), p.307-310	en
heal.abstract	The increasing clinical importance of drug-resistant bacterial pathogens has lent additional urgency to microbiological and antibacterial research. New indolic derivatives of triazoles, thiadiazoles and their respective open-chain thiosemicarbazides were evaluated for antibacterial and antifungal activity. The microorganisms used were the Gram-negative bacteria Escherichia coli ATCC 35218 and Pseudomonas aeruginosa ATCC 27853, the Gram-positive bacteria Staphylococcus aureus ATCC 25923 and Bacillus subtilis BBL 12084 and the yeasts Candida and Saccharomyces cerevisiae ATCC 2366. The most potent compounds were indole derivatives (12a-c) bearing 1,2,4-triazo-thien-5-yl moiety, which exhibit interesting antibacterial and antifungal activities.	en
heal.publisher	Thieme	en
heal.journalName	Arzneimittel-Forschung	de
heal.journalName	Drug Research	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false