In a Text-to-Speech system based on time-domain techniques that employ pitch-synchronous manipulation of the speech waveforms, one of the most important issues that affect the output quality is the way the analysis points of the speech signal are estimated and the actual points, i.e. the analysis pitchmarks. In this paper we present our methodology for calculating the pitchmarks of a speech waveform, a pitchmark detection algorithm, which after thorough experimentation and in comparison with other algorithms, proves to behave better with our TD-PSOLA-based Text-to-Speech synthesizer (Time-Domain Pitch-Synchronous Overlap Add Text to Speech System).