The calculation of the minimum number of daily number of daily normal results in order their value to be used as a quality control method

dc.contributor.author	Καρκαλούσος, Πέτρος	el
dc.contributor.author	Ψαράκης, Σ.	el
dc.date.accessioned	2015-05-03T11:19:27Z
dc.date.issued	2015-05-03
dc.identifier.uri	http://hdl.handle.net/11400/9551
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.bclf.info/	en
dc.source	http://users.teiath.gr/petef/Web_CV/Presentations/Pre_AON_2007.htm	el
dc.subject	Medical laboratory technology
dc.subject	Average Of Normals
dc.subject	Τεχνολογία ιατρικών εργαστηρίων
dc.subject	Ημερήσια μέση τιμή
dc.title	The calculation of the minimum number of daily number of daily normal results in order their value to be used as a quality control method	en
heal.type	conferenceItem
heal.classification	Medicine
heal.classification	Technology
heal.classification	Ιατρική
heal.classification	Τεχνολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://zbw.eu/stw/descriptor/10470-6
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Τεχνολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh86002225
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2006
heal.bibliographicCitation	Karkalousos, P. and Psarakis, S. (2006) The calculation of the minimum number of daily number of daily normal results in order their value to be used as a quality control method. In "14th Balkan Conference of Clinical Chemistry". Sofia: Balkan Clinical Laboratory Federation.	en
heal.abstract	Purpose: The “Average Of Normals” (AON) method has been proposed since 60’s as an alternative quality control method. According to this method the average of the daily normal results must be varied within certain limits. The violation of these limits results to analytical systematic error. The purpose of this study is to find the minimum number (N) of normal results for which their mean value can be used as a substitute of the common control samples. Former studies proved that this number depends on the ratio Sp/Sa where Sp is the variance between health people and Sa is the analytical variance. Method: A specific software was constructed based on a large number of simulations according to different analytes, minimum numbers N, human variance (Sp), analytical variance (Sa), control chart limits (L) and the truncation limits of the normal results (T). Results: Many different cases of Sp/Sa were studied. The relations between Sp/Sa and minimum N for the detection of analytical systematic error of the size of two standard deviations with probability 0,9 are: 1 to 5, 2 to 15, 3 to 32, 4 to 47, 5 to 80, 6 to 170, 7 to 210, 8 > 300. For instance: Τ3 (N=5), Τ4 (N=90), TSH (N=210), Chol (N=210), GOT (N=320). Conclusions: The number N depends on L, T and Sp/Sa. Because L and T are constants and the variance Sa is extremely small on the modern analyzers, the number N depends mostly on the Sp value or better on the reference values of the analyte.	en
heal.publisher	Balkan Clinical Laboratory Federation	en
heal.fullTextAvailability	false
heal.conferenceName	14th Balkan Conference of Clinical Chemistry	en
heal.conferenceItemType	abstract