Integron-associated antimicrobial resistance in isolates of members of Enterobacteriaceae causing community-acquired urinary infections

dc.contributor.author	Dakic, Ivana	en
dc.contributor.author	Λιλάκος, Κωνσταντίνος	el
dc.contributor.author	Svabic-Vlahovic, Milena	en
dc.contributor.author	Χριστοφιλοπούλου, Σοφία	el
dc.contributor.author	Πόγγας, Νικόλαος Γ. (1949- )	el
dc.date.accessioned	2015-05-07T16:55:39Z
dc.date.issued	2015-05-07
dc.identifier.uri	http://hdl.handle.net/11400/9844
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://informahealthcare.com/journal/mdi	en
dc.subject	Integrons
dc.subject	antibiotic resistance
dc.subject	Enterobacteriaceae
dc.subject	Urinary tract infection
dc.subject	Ιντεγκρόνια
dc.subject	Αντιβιωτική αντοχή
dc.subject	Εντεροβακτήρια
dc.subject	Ουρολοίμωξη
dc.title	Integron-associated antimicrobial resistance in isolates of members of Enterobacteriaceae causing community-acquired urinary infections	en
heal.type	journalArticle
heal.classification	Medicine
heal.classification	Microbiology
heal.classification	Ιατρική
heal.classification	Μικροβιολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh00006614
heal.classificationURI	http://skos.um.es/unescothes/C02502
heal.classificationURI	N/A-Ιατρική
heal.classificationURI	N/A-Μικροβιολογία
heal.keywordURI	http://lod.nal.usda.gov/10184
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85044079
heal.contributorName	Χάρβαλου, Αικατερίνη	el
heal.identifier.secondary	DOI: 10.1080/08910600701442773
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2007
heal.bibliographicCitation	Dakic, I., Lilakos, D., Svabic-Vlahovic, M., Christofilopoulou, S., Poggas, N., et al. (2007) Integron-associated antimicrobial resistance in isolates of members of Enterobacteriaceae causing community-acquired urinary infections. "Microbial Ecology in Health and Disease", 19 (3), p. 201-206. Available from: http://informahealthcare.com/doi/abs/10.1080/08910600701442773 [Accessed: 06/05/2015].	en
heal.abstract	The present study investigated 73 isolates of Enterobacteriaceae obtained from urine samples of outpatients for the presence of integrons and analysed the association between integrons and antimicrobial susceptibility. Resistance to one or two antibiotics belonging to different classes was found in 28 (38.4%) of the isolates, resistance to three or more antimicrobial agents with different mechanism of action, i.e. multidrug resistance in 37 (50.7%), while 8 (10.9%) were fully susceptible. The presence of integrons was shown in 13 (17.8%) of the strains tested: 9 (12.3%) carried a class 1 integron, 2 (2.7%) carried a class 2 integron, and 2 (2.7%) had both class 1 and class 2 integrons. Class 1 integron was clearly predominant, since 11 (84.6%) of 13 integron-positive isolates carried this class. No class 3 integron-positive isolates were detected. The association between the presence of an integron and multidrug resistance was highly significant (p<0.001). Integron-positive isolates were also more likely to be resistant to amoxicillin-clavulanic acid, co-trimoxazole, chloramphenicol, ciprofloxacin, norfloxacin, nalidixic acid, tetracycline and doxycycline. Five strains (45.5%) with class 1 integron were positive for the mercury resistance gene, merA, indicating the role of Tn21 transposon in dissemination of integrons within the samples studied.	en
heal.publisher	Informa Healthcare	en
heal.journalName	Microbial Ecology in Health and Disease	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false