Maternal-neonatal amino acid blood levels in relation to the mode of delivery

dc.contributor.author	Σούλπη, Κλεοπάτρα	en
dc.contributor.author	Βλάχος, Γεώργιος	el
dc.contributor.author	Παπακωνσταντίνου, Ευάγγελος Δ.	el
dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.contributor.author	Βλάχος, Δημήτριος	el
dc.date.accessioned	2015-05-07T23:16:31Z
dc.date.available	2015-05-07T23:16:31Z
dc.date.issued	2015-05-08
dc.identifier.uri	http://hdl.handle.net/11400/9906
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.ncbi.nlm.nih.gov/pubmed/19023679?dopt=AbstractPlus	en
dc.subject	Αμινοξέα
dc.subject	πρωτεόλυση
dc.subject	νεογέννητο
dc.subject	διανομή
dc.subject	οξίδωση
dc.subject	Amino acids
dc.subject	proteolysis
dc.subject	delivery
dc.subject	newborn
dc.subject	Oxidation, Physiological
dc.title	Maternal-neonatal amino acid blood levels in relation to the mode of delivery	en
heal.type	journalArticle
heal.classification	Gynecology
heal.classification	Clinical biochemistry
heal.classification	Γυναικολογία
heal.classification	Κλινική βιοχημεία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85058092
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85027062
heal.classificationURI	N/A-Γυναικολογία
heal.classificationURI	N/A-Κλινική βιοχημεία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85004486
heal.keywordURI	http://lod.nal.usda.gov/32271
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85096309
heal.contributorName	Ρώμα, Ελευθερία	el
heal.contributorName	Αντσακλής, Αριστείδης	el
heal.contributorName	Παπασωτηρίου, Ιωάννης	el
heal.contributorName	Τσακίρης, Στυλιανός	el
heal.identifier.secondary	DOI: 10.1080/00016340802578098
heal.language	en
heal.access	campus
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2009-01
heal.bibliographicCitation	Schulpis, K.H., Vlachos, G.D., Papakonstantinou, E.D., Karikas, G.A., Vlachos, D.G. et al. (2009) Maternal–neonatal amino acid blood levels in relation to the mode of delivery. Acta Obstetricia et Gynecologica Scandinavica. [Online] 88 (1). pp.71-76. Available from: http://www.ncbi.nlm.nih.gov [Accessed 07/05/2015]	en
heal.abstract	Objective. To investigate the effect of the mode of delivery on maternal–neonatal amino acid levels as high blood levels of some amino acids are implicated with endurance exercise. Design. Comparative study. Sample. Thirty women in normal pregnancy divided into two groups: Group A (n = 15) with normal labor and vaginal delivery and group B (n = 15) with scheduled cesarean section. Material and methods. Blood was obtained from the mothers pre- versus post-delivery as well as from the umbilical cord. Routine laboratory tests (liver enzymes, muscle enzyme, etc.) and the amino acid blood levels were measured with a clinical chemistry analyzer and tandem mass spectrometry methods, respectively. Results. Routine laboratory tests and the amino acid blood levels were similar in the two groups of mothers pre-delivery. Total antioxidant status levels were reduced, whereas the branched-chain amino acids (BCAAs) and alanine levels were remarkably elevated in the sera of group A post – delivery, whereas they remained unaltered in group B at the same time of study. The mentioned BCAAs and alanine levels were higher in the umbilical cord blood of group A than those in group B. The rest of the amino acids were similar. Conclusions. The increased BCAAs and alanine blood levels in mothers of group A may be related to uterine and skeletal muscle contractions during the vaginal delivery process and the high levels in the umbilical cord blood of their neonates may mirror those of the mothers. The elevation of BCAAs both in mothers of group A and their neonates may exclude or minimize tyrosine and tryptophane levels from entry in the brain resulting in decreased biogenic amine and increased prolactin production in the central nervous system of these mothers and their infants.	en
heal.publisher	Informa Healthcare	en
heal.journalName	Acta Obstetricia et Gynecologica Scandinavica	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	true