The effect of the mode of delivery on maternal-neonatal interleukin-6, biogenic amine and their precursor amino acid concentrations

dc.contributor.author	Σούλπη, Κλεοπάτρα	el
dc.contributor.author	Βλάχος, Γεώργιος	el
dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.contributor.author	Παπακωνσταντίνου, Ευάγγελος Δ.	el
dc.contributor.author	Βλάχος, Δημήτριος	el
dc.date.accessioned	2015-05-07T23:41:14Z
dc.date.issued	2015-05-08
dc.identifier.uri	http://hdl.handle.net/11400/9907
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.degruyter.com/view/j/cclm.2008.46.issue-11/cclm.2008.305/cclm.2008.305.xml	en
dc.subject	βιογενείς αμίνες
dc.subject	κατεχολαμίνες
dc.subject	διανομή
dc.subject	5-υδροξυ-τρυπταμίνη
dc.subject	ιντερλευκίνη
dc.subject	νεογέννητο
dc.subject	Biogenic amines
dc.subject	Catecholamines
dc.subject	delivery
dc.subject	5-hydroxy-tryptamine (5-HT)
dc.subject	Interleukin-6
dc.subject	newborn
dc.title	The effect of the mode of delivery on maternal-neonatal interleukin-6, biogenic amine and their precursor amino acid concentrations	en
heal.type	journalArticle
heal.classification	Clinical chemistry
heal.classification	Gynecology
heal.classification	Χημεία, Κλινική
heal.classification	Γυναικολογία
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85023014
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85058092
heal.classificationURI	N/A-Χημεία, Κλινική
heal.classificationURI	N/A-Γυναικολογία
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85014143
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85020986
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh92001229
heal.contributorName	Παπασωτηρίου, Ιωάννης	el
heal.contributorName	Αντσακλής, Αριστείδης	el
heal.contributorName	Τσακίρης, Στυλιανός	el
heal.identifier.secondary	ISSN: 1437-4331
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2008-11
heal.bibliographicCitation	Schulpis, K.H., Vlachos, G.D., Karikas, G.A., Papakonstantinou, E.D., Vlachos, D.G. et al. (2008) The effect of the mode of delivery on maternal-neonatal interleukin-6, biogenic amine and their precursor amino acid concentrations. Clinical Chemistry and Laboratory Medicine. [Online] 46 (11). pp.1624-1630. Available from: http://www.degruyter.com [Accessed 07/05/2015]	en
heal.abstract	Background: Biogenic amine, adrenaline, noradrenaline, dopamine and 5-hydroxy-tryptamine (5-HT) levels are related to interleukin-6 (IL-6) plasma concentrations and endurance exercise. The aim of our study was to investigate the effect of the mode of delivery on maternal-neonatal IL-6, biogenic amine and their precursor amino acid levels. Methods: Some women with normal pregnancy (n=56) were divided into two groups: group A (n=26) with normal labor and vaginal delivery, and group B (n=30) with scheduled cesarean section. Blood was obtained from the mothers at the beginning of labor and immediately after delivery (pre- vs. post-delivery), as well as from the umbilical cord (CB). Total antioxidant status (TAS) and IL-6 levels were measured with commercial kits, the precursor amino acids, tyrosine and tryptophan with tandem mass spectrometry and the biogenic amine blood levels with HPLC methods, respectively. Results: TAS, IL-6, biogenic amine and their precursor amino acid blood levels were similar in the two groups of mothers pre-delivery. TAS levels were reduced, whereas the amino acids, the catecholamine, 5-HT and IL-6 levels were increased post-delivery and in the CB of group A and unaltered in group B at the same time of the study. Conclusions: During a vaginal delivery process, the low TAS, the increased levels of the studied amino acids, the catecholamines, 5-HT and IL-6 may be due to the activation of the neuroendocrine system and the participation of skeletal and uterine muscles. The mode of delivery may be taken into account when IL-6 plasma levels are evaluated as an anti-inflammatory index perinatally.	en
heal.journalName	Clinical Chemistry and Laboratory Medicine (CCLM)	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false