Study of DNA interactions with melphalan, busulphan, and analogues using an HPLC method

dc.contributor.author	Καρίκας, Γεώργιος-Αλβέρτος	el
dc.contributor.author	Μαγκριώτη, Βικτώρια	el
dc.contributor.author	Κωνσταντίνου-Κόκοτου, Βιολέτα	el
dc.contributor.author	Κοκοτός, Γιώργος	el
dc.date.accessioned	2015-05-09T20:34:36Z
dc.date.issued	2015-05-09
dc.identifier.uri	http://hdl.handle.net/11400/10049
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.source	http://www.researchgate.net/publication/233043848_Study_of_DNA_interactions_with_melphalan_busulphan_and_analogues_using_an_HPLC_method	en
dc.subject	μέθοδος HPLC
dc.subject	αλκυλιωτικοί παράγοντες
dc.subject	δεοξυριβονουκλεϊκό οξύ
dc.subject	χρωματογραφικά δεδομένα
dc.subject	HPLC method
dc.subject	Alkylating agents
dc.subject	DNA
dc.subject	chromatographic data
dc.title	Study of DNA interactions with melphalan, busulphan, and analogues using an HPLC method	en
heal.type	journalArticle
heal.classification	Χημεία
heal.classification	Τεχνολογία
heal.classification	Chemistry
heal.classification	Technology
heal.classificationURI	N/A-Χημεία
heal.classificationURI	N/A-Τεχνολογία
heal.classificationURI	http://skos.um.es/unescothes/C00568
heal.classificationURI	http://id.loc.gov/authorities/subjects/sh85133147
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh88002246
heal.keywordURI	http://id.loc.gov/authorities/subjects/sh85037008
heal.identifier.secondary	DOI: 10.1081/JLC-100100457
heal.dateAvailable	10000-01-01
heal.language	en
heal.access	forever
heal.recordProvider	Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων	el
heal.publicationDate	2000
heal.bibliographicCitation	Karikas, G., Magrioti, V., Constantinou, V. and Kokotos, G. (2000) Study of DNA interactions with busulphan, melphalan and analogues using an HPLC method. Journal of Liquid Chromatography & Related Technologies. [Online] 23 (12), pp.1859-1864. Available from: http://www.researchgate.net [Accessed 09/05/2015]	en
heal.abstract	A simple reversed phase HPLC method suitable to study the interactions of alkylating agents with DNA is presented in this paper. DNA interaction is expressed as the % DNA peak size exclusion. The effects caused by the antitumor drugs melphalan, busulphan, and busulpan analogues on DNA were clearly observed through chromatographic data. The synthetic dimethanesulphonates of 2-tetradecyl-1,4-butanediol and 1,2-hexadecanediol were proved more potent than busulphan. Study of DNA interactions with melphalan, busulphan, and analogues using an HPLC method - ResearchGate. Available from: http://www.researchgate.net/publication/233043848_Study_of_DNA_interactions_with_melphalan_busulphan_and_analogues_using_an_HPLC_method [accessed May 9, 2015].	en
heal.journalName	Journal of Liquid Chromatography & Related Technologies	en
heal.journalType	peer-reviewed
heal.fullTextAvailability	false