E-learning is becoming more and more prominent, supporting the improvement of both synchronous and asynchronous learning. The impressive development of the Information and Communication Technologies has made available to higher education the infrastructure that permits universities to fulfil the increasing requirements for academic electronic services. The most widespread asynchronous e-learning tools are the learning management systems, the web-based platforms that offer instructors an easy to use environment suitable for managing and delivering educational content for their courses, but which can also be used for communication between instructors and students. During the last three years, the Department of Informatics of the TEI of Athens is using an asynchronous e-learning platform, called cs e-Class, to enhance traditional classroom instruction by incorporating a number of online activities. In this article, we present our experience from the use of that platform and discuss the success of its adaptation to the educational and administrative needs of our department. We compare it with an independent but similar approach that is being used at the Department of Informatics of the Universidade Nova de Lisboa.