This paper describes a working example of mapping cultural heritage information and data from the National Gallerycollectionin London.The paper discusses the process of semantically representing and enriching the available cultural heritage data, and reveals the challenges of semantically expressing interrelations and groupings among the physicalitems, the venueand the available digital resources.The paper also highlights the challenges in the creation ofthe conceptual model of the National Gallery asa Venue, which aims toi) describe and understand the correlation between the parts of a building and the whole; ii) to record and express the semantic relationships among the building components with the building as a whole; and iii) to be able to record the accurate location of objects within space and capture their provenance in terms of changes of location. The outcome of this investigation is the proposed fully CIDOC-CRM compliant structure,thathas been developed during the CrossCult project, the CrossCult Venue Ontology, whichattempts to model the spatial arrangements of the different venues that participate as demonstrators in the project:an indoor gallery,asmall museum, four open air archaeological sitesand two cities.