Coastal areas face many challenges due to a number of unique characteristics that make them very vulnerable and in need of protection. On the other hand, the study of coastal areas through indicators is strongly recommended by the international bodies devoted to spatial planning and integrated coastal management. In this context, “Anthropogenetic Intensity” is a spatial indicator that aims to measure the human impact on coastal areas, by calculating the total volume of man-made activities. It aims to reveal the degree of economic activities along a coast, the intensity of land uses and the total landscape annoyance caused by human involvement. In order to study and finally measure the “Anthropogenetic Intensity”, the “mean height” of buildings and all other constructions on a coastal area, at a specific point of time, can be used. The critical point is not only the selection of the appropriate land uses/covers classification but the weights with which each of the uses/covers will be endowed. Moreover, “Anthropogenetic Intensity” indicator may have extra weights related to other parameters, as the distance from the shoreline. The “Anthropogenetic Intensity” indicator aspires to provide enough information about the coastal environment in order to improve the available spatial data and to assist all the involved stakeholders and policy makers in their strategies for integrated management and sustainable development. The most important and valuable results can derive from the differences of “Anthropogenetic Intensity” values at the same coast, at two different periods of time or at different coasts, at the same time. The magnitude of those differences can be used as an alert to activate already established mechanisms in order to control the land exploitation and organize the related reactions, in the context of coastal land use policy. This proposed indicator is recently launched in the framework of AMICA (“Appraisal of manmade interventions along the Hellenic coastal areas”), a research project of the Spatial Analysis Lab., Technological Educational Institute (TEI) of Athens. Into the same framework, several case studies are under realization in order to test the effectiveness of the indicator and to define the critical and marginal values it may have.