In the present investigation, two novel gum mixtures were evaluated as controlled
release polymer. The ghatti gum obtained from Anogeissus latifolia and Konjac
glucomannan from Amorphophallus konjac was evaluated as base polymer for
controlled delivery of model drug diclofenac sodium. The prepared synergistically
acting gums were evaluated for compatibility study using FT-IR. The diclofenac
sodium tablets were evaluated for hardness, friability, weight variation and drug
content. The in vitro dissolution study confirmed that the controlled release behavior
is mainly due to konjac glucomannan proportion and optimum concentration ratio for
ghatti: konjac glucomannan was 30:70.